NF-1X Inhibitors
NF-1X inhibitors represent a distinct class of chemical compounds designed for the specific purpose of modulating the activity of NF-1X, a molecular target of interest in various research areas, particularly in the field of molecular biology and cell signaling. These inhibitors are characterized by their ability to interact selectively with NF-1X, a protein or enzyme involved in cellular processes critical for normal cell function. NF-1X itself is a member of the NF-1 family of proteins, which play a crucial role in signal transduction pathways and gene expression regulation within cells.
The design and development of NF-1X inhibitors typically involve the synthesis of small molecules with specific structural features that enable them to bind to NF-1X, either blocking or modulating its activity. These compounds are often the result of extensive medicinal chemistry efforts, where researchers manipulate the chemical structure of these inhibitors to enhance their binding affinity and selectivity for NF-1X. Understanding the structural and mechanistic aspects of NF-1X inhibitors is essential for researchers seeking to unravel the intricacies of cellular signaling pathways and the regulation of gene expression, as NF-1X is known to exert significant influence in these processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib is a proteasome inhibitor that indirectly inhibits NF-kappa B (NF-κB) by preventing the degradation of I kappa B (IκB), an inhibitor of NF-κB. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $41.00 | 4 | |
Aspirin is a common non-steroidal anti-inflammatory drug (NSAID) that can inhibit NF-κB activation by suppressing the activity of IκB kinase. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Thalidomide and its analogs, such as lenalidomide and pomalidomide, are studied in the research of multiple myeloma and have anti-inflammatory effects, partly by inhibiting NF-κB. | ||||||
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $60.00 $75.00 $125.00 $205.00 | 8 | |
Sulfasalazine is used for inflammatory bowel disease (IBD) and rheumatoid arthritis. It can inhibit NF-κB activation. | ||||||
Z-Guggulsterone | 39025-23-5 | sc-204414B sc-204414 sc-204414A | 5 mg 10 mg 25 mg | $189.00 $362.00 $719.00 | 28 | |
Guggulsterone is a natural compound found in the resin of the guggul tree. It has been shown to inhibit NF-κB and has potential anti-inflammatory properties. | ||||||
Andrographolide | 5508-58-7 | sc-205594 sc-205594A | 50 mg 100 mg | $15.00 $39.00 | 7 | |
This natural compound from the plant Andrographis paniculata has anti-inflammatory effects and inhibits NF-κB activation. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is a flavonoid found in various fruits and vegetables. It can inhibit NF-κB signaling and has anti-inflammatory properties. | ||||||
Auranofin | 34031-32-8 | sc-202476 sc-202476A sc-202476B | 25 mg 100 mg 2 g | $150.00 $210.00 $1899.00 | 39 | |
Auranofin is a gold-containing compound studied in the research of rheumatoid arthritis. It can inhibit NF-κB activation. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Bay 11-7082 is a synthetic compound that specifically inhibits the activation of NF-κB. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $79.00 $300.00 | 32 | |
Parthenolide is a natural compound found in feverfew. It inhibits NF-κB by directly targeting IκB kinase. | ||||||