Date published: 2026-4-1

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NF-1A Inhibitors

NF-1A inhibitors, a class of chemical compounds, are designed to specifically target and modulate the activity of the NF-1A protein. NF-1A, short for Nuclear Factor 1A, is a transcription factor that plays a crucial role in gene expression regulation. Transcription factors like NF-1A bind to DNA sequences and control the initiation of gene transcription, which ultimately determines the production of specific proteins within a cell. NF-1A, in particular, is known to be involved in various cellular processes, including development, differentiation, and immune responses. To achieve these regulatory functions, NF-1A interacts with DNA by binding to specific binding sites known as NF-1A response elements (NREs), usually located in the promoter regions of target genes. NF-1A inhibitors work by interfering with the binding of NF-1A to its target DNA sequences. This disruption in the protein-DNA interaction can lead to a downregulation or suppression of the expression of genes that are normally regulated by NF-1A. The development of NF-1A inhibitors is of significant interest in the field of molecular biology and genetics as they provide a valuable tool for studying gene function and regulation.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin is a natural compound found in turmeric that has been studied for its potential to inhibit NF-1A activity. It has antioxidant and anti-inflammatory properties and may modulate NF-1A's function.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is a polyphenol found in red grapes and wine. It has been investigated for its ability to inhibit NF-1A and has shown promise in various research studies.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG is a bioactive compound found in green tea. It has antioxidant properties and has been suggested to inhibit NF-1A activity, potentially contributing to its health benefits.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin is a flavonoid present in various fruits and vegetables. It has been studied for its potential to inhibit NF-1A and is considered to have anti-inflammatory and antioxidant effects.

Reserpine

50-55-5sc-203370
sc-203370A
1 g
5 g
$137.00
$414.00
1
(2)

Reserpine is a naturally occurring alkaloid that has been explored for its NF-1A inhibitory properties. It is primarily used as an antipsychotic agent in research but may have other applications.

Berberine

2086-83-1sc-507337
250 mg
$92.00
1
(0)

Berberine is an alkaloid found in several plants, including goldenseal and barberry. It has been investigated for its potential to inhibit NF-1A and has shown promise in controlling certain diseases.

Silybin

22888-70-6sc-202812
sc-202812A
sc-202812B
sc-202812C
1 g
5 g
10 g
50 g
$55.00
$114.00
$206.00
$714.00
6
(1)

Silibinin is a flavonolignan found in milk thistle seeds. It has been studied for its potential to inhibit NF-1A and has antioxidant and hepatoprotective properties.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein is an isoflavone found in soybeans and soy products. It has been investigated for its ability to modulate NF-1A activity.

Ellagic Acid, Dihydrate

476-66-4sc-202598
sc-202598A
sc-202598B
sc-202598C
500 mg
5 g
25 g
100 g
$58.00
$95.00
$245.00
$727.00
8
(1)

Ellagic acid is a polyphenol found in various fruits and nuts. It has been explored for its NF-1A inhibitory properties and potential anticancer effects.

Andrographolide

5508-58-7sc-205594
sc-205594A
50 mg
100 mg
$15.00
$40.00
7
(1)

Andrographolide is a compound found in the plant Andrographis paniculata. It has been studied for its anti-inflammatory properties and its potential to inhibit NF-1A.