Neu Inhibitors
Items 11 to 20 of 35 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tyrphostin AG 879 | 148741-30-4 | sc-3557 sc-3557A | 5 mg 25 mg | $83.00 $328.00 | 4 | |
Tyrphostin AG 879 is a potent compound that showcases unique reactivity patterns as an acid halide. It engages in selective nucleophilic attacks, allowing for the formation of diverse acyl derivatives. The compound's electronic structure enhances its electrophilic character, resulting in accelerated reaction rates with various nucleophiles. Its solubility in polar and non-polar solvents facilitates versatile reaction environments, making it a valuable participant in complex synthetic reactions. | ||||||
Lapatinib-13C2,15N Ditosylate | sc-280905 | 500 µg | $330.00 | |||
Lapatinib-13C2,15N Ditosylate exhibits distinctive reactivity as a Neu, characterized by its ability to form stable complexes with specific biomolecules. Its isotopic labeling provides insights into metabolic pathways, enabling detailed kinetic studies. The compound's unique steric and electronic properties influence its interaction dynamics, allowing for selective binding and modulation of target interactions. This behavior enhances its utility in exploring molecular mechanisms and reaction pathways. | ||||||
(±)-Baclofen | 1134-47-0 | sc-200464 sc-200464A | 1 g 5 g | $55.00 $253.00 | ||
Baclofen, a GABA-B receptor agonist, directly influences the GABAergic neurotransmitter system. By activating GABA-B receptors, Baclofen inhibits the release of GABA, an inhibitory neurotransmitter. The modulation of GABAergic neurotransmission can have widespread effects on neuronal communication, impacting overall brain function. | ||||||
Tyrphostin B42 | 133550-30-8 | sc-3556 | 5 mg | $26.00 | 4 | |
Tyrphostin B42 functions as a Neu by selectively inhibiting receptor tyrosine kinases, showcasing a unique ability to disrupt signaling cascades. Its structural conformation allows for precise interactions with ATP-binding sites, influencing phosphorylation processes. The compound's kinetic profile reveals rapid binding and dissociation rates, facilitating real-time studies of cellular signaling. Additionally, its hydrophobic regions enhance membrane permeability, impacting its interaction with lipid environments. | ||||||
AG 825 | 149092-50-2 | sc-202045 sc-202045A sc-202045B sc-202045C | 2 mg 5 mg 10 mg 100 mg | $46.00 $92.00 $179.00 $1734.00 | ||
AG 825 acts as a Neu by targeting specific protein interactions, particularly through its ability to modulate dimerization of receptor tyrosine kinases. Its unique structural features enable it to engage in hydrogen bonding and hydrophobic interactions, influencing downstream signaling pathways. The compound exhibits a distinct kinetic behavior, characterized by a slow onset of action, allowing for prolonged effects on cellular processes. Its solubility properties further enhance its distribution within biological systems, affecting its overall bioavailability. | ||||||
EGFR/ErbB-2 Inhibitor Inhibitor | 179248-61-4 | sc-203935 | 1 mg | $101.00 | ||
EGFR/ErbB-2 Inhibitor functions as a Neu by selectively disrupting the conformational dynamics of receptor tyrosine kinases. Its unique binding affinity facilitates the stabilization of inactive receptor states, preventing aberrant signaling cascades. The compound's intricate molecular architecture promotes specific electrostatic interactions, enhancing its selectivity. Additionally, its kinetic profile reveals a gradual dissociation rate, contributing to sustained modulation of cellular responses. | ||||||
TAK 165 | 366017-09-6 | sc-361372 sc-361372A | 10 mg 50 mg | $139.00 $781.00 | ||
TAK 165 acts as a Neu by engaging in selective allosteric modulation of receptor tyrosine kinases. Its unique structural features enable it to induce conformational changes that favor inactive receptor states, effectively curbing unwanted signaling. The compound exhibits distinctive hydrophobic interactions that enhance binding specificity, while its reaction kinetics demonstrate a prolonged residence time on target sites, ensuring a durable impact on receptor activity. | ||||||
JNJ 28871063 hydrochloride | 944341-54-2 | sc-204025 sc-204025A | 10 mg 50 mg | $215.00 $880.00 | 1 | |
JNJ 28871063 hydrochloride functions as a Neu through its ability to selectively inhibit dimerization of receptor tyrosine kinases. Its unique binding profile allows for specific interactions with key residues, stabilizing inactive conformations. The compound's distinct electrostatic properties facilitate strong affinity for target sites, while its kinetic behavior showcases rapid association and slow dissociation rates, contributing to sustained modulation of receptor function. | ||||||
Reserpine | 50-55-5 | sc-203370 sc-203370A | 1 g 5 g | $134.00 $406.00 | 1 | |
Reserpine indirectly influences neurotransmission by inhibiting the vesicular monoamine transporter (VMAT). This inhibition leads to the depletion of monoamine neurotransmitters, including dopamine, norepinephrine, and serotonin, from synaptic vesicles. The resultant decrease in neurotransmitter availability affects neuronal signaling and overall neurotransmission. | ||||||
2′-Thioadenosine | 60239-18-1 (non-salt) | sc-220826 | 2 mg | $270.00 | ||
2'-Thioadenosine acts as a Neu by engaging in unique molecular interactions that disrupt nucleotide binding and signaling pathways. Its sulfur substitution enhances stability and alters conformational dynamics, allowing for selective modulation of enzymatic activity. The compound exhibits distinctive reaction kinetics, characterized by a rapid formation of enzyme complexes and a gradual release, which influences downstream signaling cascades. Its solubility and reactivity profile further contribute to its role in cellular processes. | ||||||