NCKX5 Activators
NCKX5 activators are a class of chemicals that can potentially influence the activity of the NCKX5 protein, which is a potassium-dependent sodium-calcium exchanger. These chemicals primarily work through interfering with the transport of ions across the plasma membrane, which indirectly affects the function of NCKX5.
NCKX5 activators inhibit the Na+/K+-ATPase. These inhibitors increase intracellular sodium concentrations, which can potentiate the function of sodium-calcium exchangers like NCKX5. By increasing intracellular sodium or equalizing potassium ions across the plasma membrane, they may indirectly enhance the function of NCKX5. Activators of this class can reduce intracellular calcium concentrations, which might indirectly stimulate the sodium-calcium exchange function of NCKX5.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ouabain-d3 (Major) | sc-478417 | 1 mg | $516.00 | |||
Ouabain inhibits Na+/K+-ATPase, leading to increased intracellular sodium concentrations. This can potentiate the function of sodium-calcium exchangers like NCKX5. | ||||||
12β-Hydroxydigitoxin | 20830-75-5 | sc-213604 sc-213604A | 1 g 5 g | $143.00 $694.00 | ||
12β-Hydroxydigitoxin is another Na+/K+-ATPase inhibitor. By increasing intracellular sodium, it can indirectly enhance NCKX5 activity. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin is a sodium ionophore that increases intracellular sodium concentrations, which can amplify the function of sodium-calcium exchangers like NCKX5. | ||||||
Nigericin sodium salt | 28643-80-3 | sc-201518A sc-201518 sc-201518B sc-201518C sc-201518D | 1 mg 5 mg 25 mg 1 g 5 g | $46.00 $112.00 $240.00 $7079.00 $27417.00 | 9 | |
Nigericin is a potassium ionophore. By equalizing the concentration of potassium ions across the plasma membrane, it may indirectly enhance the function of NCKX5. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
Verapamil is a calcium channel blocker that reduces intracellular calcium concentrations, which might indirectly stimulate the sodium-calcium exchange function of NCKX5. | ||||||
Amlodipine | 88150-42-9 | sc-200195 sc-200195A | 100 mg 1 g | $74.00 $166.00 | 2 | |
Amlodipine is a calcium channel blocker that reduces intracellular calcium concentrations, which may indirectly enhance the function of NCKX5. | ||||||
Nicardipine hydrochloride | 54527-84-3 | sc-202731 sc-202731A | 1 g 5 g | $33.00 $83.00 | 5 | |
Nicardipine is a calcium channel blocker that reduces intracellular calcium concentrations, which may indirectly enhance the function of NCKX5. | ||||||