NBEAL1 Inhibitors
NBEAL1 Inhibitors target various aspects of cellular trafficking, vesicle formation, and hematopoietic cell functions, potentially influencing the functional context of NBEAL1. Given NBEAL1's involvement in vesicular trafficking and granule biogenesis, modulation of these pathways could indirectly impact its activity. Compounds such as Brefeldin A, Monensin Sodium Salt, and Dynamin Inhibitor I, Dynasore, which affect vesicle trafficking and scission, can indirectly influence processes in which NBEAL1 is implicated. Disruptors of the cytoskeleton, like Nocodazole, Cytochalasin D, Vinblastine, Latrunculin A, Latrunculia magnifica, and Colchicine, can also impact vesicular dynamics and cellular transport mechanisms, potentially affecting NBEAL1's function.
Inhibitors of clathrin-mediated endocytosis and PI3K inhibitors like Wortmannin provide insights into the broader context of vesicle formation and trafficking, where NBEAL1 might play a role. Additionally, compounds influencing hematopoietic processes, such as Erythropoietin and G-CSF, could indirectly affect granule formation and maturation processes related to NBEAL1. These compounds, while not directly targeting NBEAL1, are important for understanding the complex processes of vesicle trafficking, granule biogenesis, and hematopoietic cell functions.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A disrupts vesicle trafficking by inhibiting the exchange of guanine nucleotide on ARF proteins, potentially affecting processes related to NBEAL1. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Monensin is an ionophore that disrupts intracellular ion gradients and can impact vesicular transport, potentially influencing NBEAL1's function. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
Dynamin Inhibitor I, Dynasore inhibits the GTPase activity of dynamin, affecting vesicle scission and potentially impacting NBEAL1-related vesicular processes. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubule polymerization, potentially affecting intracellular transport and processes relevant to NBEAL1. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a PI3K inhibitor, affecting various signaling pathways that might indirectly impact vesicle formation and NBEAL1 function. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Cytochalasin D inhibits actin polymerization, which can affect cytoskeletal dynamics and potentially influence NBEAL1-related activities. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine disrupts microtubule assembly, potentially impacting cellular processes and trafficking systems involving NBEAL1. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Latrunculin A, Latrunculia magnifica binds to actin monomers and disrupts actin filament assembly, potentially influencing NBEAL1's role in vesicle trafficking. | ||||||
Pitstop 2 | 1419093-54-1 | sc-507418 | 10 mg | $360.00 | ||
Inhibitors of clathrin-mediated endocytosis, like Pitstop 2, could indirectly affect vesicular processes and NBEAL1 function. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin, inhibiting microtubule polymerization, and might indirectly impact NBEAL1-related cellular functions. | ||||||