MUP9 Inhibitors
MUP9 inhibitors are specialized compounds designed to target and inhibit Major Urinary Protein 9 (MUP9), a member of the MUP family, which is known for its role in binding and transporting pheromones in animals, particularly rodents. MUPs, including MUP9, function as molecular carriers for hydrophobic molecules, primarily pheromones, which are used in chemical signaling between individuals. These pheromones are crucial for various behaviors, such as territory marking, mating, and social recognition. Inhibiting MUP9 prevents it from binding and releasing these signaling molecules, thereby interfering with the processes involved in chemical communication within the animal's environment. This interruption of pheromone signaling can influence key behaviors linked to social interaction and dominance.
Research utilizing MUP9 inhibitors allows scientists to investigate the specific role of MUP9 in pheromone-mediated communication and behavior. These inhibitors provide valuable insights into how MUP9 functions within the broader family of MUP proteins, and how its inhibition can affect the dynamics of pheromone transport and release. By studying the impact of MUP9 inhibition on behavioral patterns, researchers can better understand the intricate biological systems that govern animal interactions and social hierarchies. Additionally, MUP9 inhibitors are used in structural studies to explore the protein's binding affinities and mechanisms at a molecular level. These insights are crucial for understanding the complex biochemical networks associated with pheromone signaling and MUP-mediated processes in various animal models.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pertussis Toxin (islet-activating protein) | 70323-44-3 | sc-200837 | 50 µg | $442.00 | 3 | |
Inhibits GPCR signaling crucial for Mup9's predicted function in the extracellular space. Pertussis Toxin disrupts GPCR signaling, indirectly inhibiting Mup9, potentially altering its role in extracellular processes. | ||||||
Batimastat | 130370-60-4 | sc-203833 sc-203833A | 1 mg 10 mg | $175.00 $370.00 | 24 | |
Targets Matrix Metalloproteinases (MMPs), influencing Extracellular Matrix (ECM) remodeling. Indirectly inhibits Mup9 by modulating ECM, potentially impacting the protein's role in the extracellular environment. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Blocks SERCA, affecting intracellular calcium homeostasis. Indirectly inhibits Mup9's predicted function in the extracellular space by influencing calcium-dependent signaling pathways. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Induces calcium influx by facilitating ion transport across the cell membrane. Ionomycin disrupts intracellular calcium homeostasis, indirectly inhibiting Mup9 in the extracellular space by influencing calcium-dependent signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K/AKT pathway associated with Mup9. LY294002 disrupts PI3K/AKT signaling, indirectly affecting Mup9 in the extracellular space and potentially modulating its predicted function. | ||||||
TAPI-1 | 171235-71-5 | sc-222337 | 1 mg | $656.00 | 15 | |
Inhibits ADAM (A Disintegrin And Metalloproteinase) family enzymes. TAPI-1 influences Extracellular Matrix (ECM) remodeling, indirectly inhibiting Mup9 by modulating the ECM in the extracellular space and potentially impacting its predicted function. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Targets the MEK/ERK pathway influencing Mup9's predicted function in the extracellular space. U0126 disrupts MEK/ERK signaling, indirectly inhibiting Mup9, potentially altering its role in extracellular processes. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $148.00 $597.00 | 75 | |
Specifically inhibits Rac1, a GTPase involved in cytoskeletal reorganization. NSC 23766 indirectly inhibits Mup9, potentially impacting its predicted function in the extracellular space by affecting GTPase signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK in the MAPK/ERK pathway associated with Mup9. PD98059 disrupts this pathway, indirectly affecting Mup9 in the extracellular space and potentially modulating its predicted function. | ||||||
GW 5074 | 220904-83-6 | sc-200639 sc-200639A | 5 mg 25 mg | $106.00 $417.00 | 10 | |
Targets Raf-1 kinase in the Ras/Raf/MEK/ERK pathway associated with Mup9. GW5074 disrupts this pathway, indirectly inhibiting Mup9, potentially altering its role in extracellular processes. | ||||||