MSMP Inhibitors primarily functions to modulate various cellular signaling pathways, related to MSMP's role or expression. Among the notable compounds in this category, Gefitinib stands out as an EGFR inhibitor. The EGFR signaling cascade is intimately connected to cellular growth, proliferation, and survival, suggesting that its modulation can indirectly influence MSMP-associated processes. Likewise, compounds such as PD98059 and U0126 are recognized for their inhibitory effects on MEK, subsequently affecting the MAPK/ERK pathway.
Furthermore, the PI3K/Akt pathway, a cornerstone for cell survival and proliferation, can be targeted using inhibitors like LY294002, Wortmannin, Ipatasertib, and ZSTK474. By adjusting this signaling axis, these inhibitors offer a strategy to influence cellular processes linked with MSMP. Rapamycin's role as an mTOR inhibitor signifies its capacity to modulate cell growth and metabolic pathways, which can be linked with MSMP. Lastly, Palbociclib's ability to inhibit CDK4/6 offers an approach to control cell cycle progression.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
EGFR inhibitor; EGFR can be involved in various signaling pathways related to cell growth and survival. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor; Affects the MAPK/ERK pathway, which plays a role in cell proliferation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor; PI3K/Akt pathway is crucial for cell survival and proliferation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor that affects cell survival and growth pathways. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAPK inhibitor; p38 MAPK is involved in inflammation and cell differentiation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor; JNK pathway plays a role in apoptosis and cell survival. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor; mTOR pathway regulates cell growth and metabolism. | ||||||
(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone | sc-501166 | 5 mg | $540.00 | |||
Akt inhibitor; Directly affects the PI3K/Akt pathway. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
CDK4/6 inhibitor; Cell cycle regulation affects cell proliferation. | ||||||
ZSTK 474 | 475110-96-4 | sc-475495 | 5 mg | $75.00 | ||
PI3K inhibitor; Affects cell survival and growth pathways. | ||||||