MRP-S15 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tetracycline | 60-54-8 | sc-205858 sc-205858A sc-205858B sc-205858C sc-205858D | 10 g 25 g 100 g 500 g 1 kg | $62.00 $92.00 $265.00 $409.00 $622.00 | 6 | |
Tetracycline binds to the 30S subunit of the mitochondrial ribosome, which is analogous to its action in bacterial cells. Since MRP-S15 is part of the mitochondrial ribosome, this can inhibit the protein's role in mitochondrial protein synthesis. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $53.00 | 10 | |
Chloramphenicol inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Given that MRP-S15 is a mitochondrial ribosomal protein, chloramphenicol can inhibit its function in protein synthesis within the mitochondria. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Dactinomycin intercalates into DNA and prevents RNA synthesis. Since MRP-S15 is involved in mitochondrial translation, its function can be inhibited by the prevention of mRNA synthesis necessary for translation. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Puromycin causes premature chain termination during translation by acting as an analog of aminoacyl-tRNA. This can inhibit the function of MRP-S15 as it is part of the mitochondrial translation machinery. | ||||||
Erythromycin | 114-07-8 | sc-204742 sc-204742A sc-204742B sc-204742C | 5 g 25 g 100 g 1 kg | $56.00 $240.00 $815.00 $1305.00 | 4 | |
Erythromycin binds to the 50S subunit of the ribosome, inhibiting translocation. As MRP-S15 is a component of the mitochondrial ribosome, its function in translation can be inhibited by erythromycin. | ||||||
Fusidic acid | 6990-06-3 | sc-215065 | 1 g | $292.00 | ||
Fusidic acid prevents the turnover of elongation factor G (EF-G) from the ribosome. MRP-S15, being a part of the mitochondrial ribosome, can have its function in translation inhibited by the stalling of EF-G. | ||||||
Doxycycline Hyclate | 24390-14-5 | sc-204734B sc-204734 sc-204734A sc-204734C | 100 mg 1 g 5 g 25 g | $26.00 $49.00 $105.00 $190.00 | 25 | |
Doxycycline inhibits protein synthesis by binding to the 30S ribosomal subunit. This action can inhibit MRP-S15's role in mitochondrial protein synthesis. | ||||||
Thiostrepton | 1393-48-2 | sc-203412 sc-203412A | 1 g 5 g | $115.00 $415.00 | 10 | |
Thiostrepton binds to the 50S ribosomal subunit and affects the GTPase activity of elongation factors. The function of MRP-S15 in the mitochondrial ribosome can be inhibited by thiostrepton's action. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide inhibits eukaryotic protein synthesis by interfering with the translocation step. While it primarily affects cytoplasmic ribosomes, at high concentrations, it may inhibit mitochondrial protein synthesis, thereby inhibiting MRP-S15 function. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin inhibits peptidyl transferase activity of the ribosome. Since MRP-S15 is involved in mitochondrial protein synthesis, its function can be inhibited by anisomycin's action on the peptidyl transferase center. | ||||||