Date published: 2026-4-24

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MOX-2 Inhibitors

MOX-2 inhibitors belong to a distinctive class of chemical compounds characterized by their ability to selectively modulate the activity of myeloid-specific oxidized LDL receptor 2 (MOX-2), a receptor primarily expressed in myeloid cells. The MOX-2 protein, also known as OLR1, plays a crucial role in cellular processes associated with oxidative stress and inflammation. These inhibitors are designed to exert their effects by interacting with MOX-2, thereby influencing downstream signaling pathways involved in cellular responses to oxidative damage and immune activation. The molecular architecture of MOX-2 inhibitors typically comprises specific structural motifs that facilitate binding to the MOX-2 receptor, leading to modulation of its activity.

MOX-2 inhibitors represents a significant advancement in the field of molecular pharmacology, offering researchers a tool to dissect the intricate pathways associated with myeloid cell function. By selectively targeting MOX-2, these inhibitors contribute to our understanding of the molecular mechanisms underlying oxidative stress-related phenomena. Additionally, their precise mode of action provides researchers with an opportunity to explore potential applications in various experimental contexts, ranging from studies on cellular signaling pathways to investigations into the broader implications of myeloid cell function. As scientists delve deeper into the complexities of MOX-2 inhibition, the hope is that this class of compounds will unveil novel insights into cellular processes and pave the way for innovative approaches in biomedical research.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Influences differentiation pathways that can regulate transcription factors including MEOX2.

Cyclopamine

4449-51-8sc-200929
sc-200929A
1 mg
5 mg
$94.00
$208.00
19
(1)

Targets the Hedgehog signaling pathway, which may intersect with MEOX2's role in development.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

PI3K inhibitor that can alter signaling pathways affecting transcription factor activity.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Inhibits MEK, which is involved in the MAPK/ERK pathway, potentially influencing MEOX2 activity.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAPK, which can affect transcription factor regulation and cellular differentiation.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Inhibits mTOR, which can influence cell growth and transcription factor activity.

Chaetocin

28097-03-2sc-200893
200 µg
$126.00
5
(1)

Disrupts HIF-1α/p300 interaction, potentially altering transcription factor dynamics.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

ROCK inhibitor, affects cytoskeletal dynamics, potentially impacting transcription factor localization.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Inhibits JNK, which could modify transcriptional regulation by MEOX2.

DAPT

208255-80-5sc-201315
sc-201315A
sc-201315B
sc-201315C
5 mg
25 mg
100 mg
1 g
$40.00
$120.00
$480.00
$2141.00
47
(3)

Notch pathway inhibitor, which may indirectly affect MEOX2-related differentiation processes.