Date published: 2025-10-6

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MOSPD1 Inhibitors

MOSPD1 inhibitors constitute a class of chemical compounds specifically designed to modulate the activity of the MOSPD1 protein. MOSPD1, or Motile Sperm Domain-Containing Protein 1, is a transmembrane protein that plays a crucial role in various cellular processes, particularly those related to cell motility, migration, and invasion. Inhibitors targeting MOSPD1 aim to interfere with its function, typically in the context of research and understanding the biological mechanisms associated with this protein. The development and use of MOSPD1 inhibitors have primarily been driven by their utility as research tools in investigating cellular processes related to cell movement and adhesion. These inhibitors are often employed in vitro and in cellular assays to elucidate MOSPD1's role in various physiological and pathological contexts. Researchers utilize MOSPD1 inhibitors to gain insights into signaling pathways and mechanisms influenced by MOSPD1, including those relevant to cancer metastasis and immune responses. By selectively inhibiting MOSPD1, scientists can explore its downstream effects on cellular behavior and identify novel targets for intervention in conditions where MOSPD1 plays a pivotal role. Overall, MOSPD1 inhibitors serve as valuable molecular probes, shedding light on the intricate molecular pathways governed by this protein and offering avenues for further biological and pharmacological exploration.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Clozapine

5786-21-0sc-200402
sc-200402A
50 mg
500 mg
$68.00
$357.00
11
(1)

Clozapine inhibits MOSPD1 by binding to its active site, thus blocking the enzyme's function in promoting cell migration and invasion. It may disrupt intracellular signaling pathways related to MOSPD1, leading to reduced cancer metastasis.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

SB-203580 inhibits MOSPD1 by inhibiting its activation and subsequent downstream signaling, which can help reduce inflammation and immune cell migration by disrupting MOSPD1's involvement in these processes.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 is a PI3K inhibitor that indirectly affects MOSPD1 by blocking the PI3K pathway. This, in turn, reduces the activation of MOSPD1 and its role in cell migration and adhesion.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin inhibits MOSPD1 by interfering with the mTOR pathway, which regulates MOSPD1 activation. Inhibition of mTOR reduces MOSPD1-mediated processes like cell motility and metastasis.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 inhibits MOSPD1 by blocking the JNK pathway, which is involved in MOSPD1 activation. This inhibition can lead to decreased cell migration and invasion, particularly in cancer cells.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Wortmannin is a PI3K inhibitor that indirectly affects MOSPD1 by disrupting PI3K-mediated signaling pathways. This leads to reduced activation of MOSPD1 and its role in cell migration and adhesion.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

U0126 inhibits MOSPD1 by targeting the MEK pathway, a downstream signaling cascade of MOSPD1. Blocking MEK activation helps reduce MOSPD1-mediated cell migration and invasion.

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$80.00
$212.00
$408.00
48
(1)

SB-431542 is a TGF-beta receptor inhibitor that indirectly affects MOSPD1 by blocking TGF-beta signaling. Inhibition of TGF-beta can reduce MOSPD1-mediated processes like cell motility and metastasis.

SB-505124

694433-59-5sc-362794
sc-362794A
10 mg
50 mg
$321.00
$1350.00
2
(0)

SB-505124 inhibits MOSPD1 by targeting the ALK4/5/7 receptor kinases involved in the TGF-beta pathway. This inhibition can lead to decreased MOSPD1-mediated cell migration and invasion.

SP2509

1423715-09-6sc-492604
5 mg
$284.00
(0)

SP2509 is a specific inhibitor of MOSPD1 that directly binds to the enzyme's active site. It disrupts MOSPD1's function, inhibiting cell migration and invasion, making it a potential anti-cancer agent.