MOK, or MAPK/MAK/MRK overlapping kinase, is a protein encoded by the MOK gene in humans. It belongs to the family of serine/threonine kinases, a group of proteins that play key roles in various cellular processes, including metabolism, cell cycle progression, and apoptosis.MOK kinase is part of the RAS subfamily. RAS proteins are involved in transmitting signals within cells, which instruct cells to grow, divide, or die. Therefore, MOK plays a crucial role in cell signaling, acting as a mediator in the process of signal transduction.
The precise biological function of MOK is not fully understood. However, studies suggest that it may be involved in cytoskeletal organization. The cytoskeleton is a network of fibers in the cell that maintains cell shape, protects the cell, and enables cellular movement.Alterations in MOK expression or function have been associated with a variety of human diseases. For instance, MOK has been implicated in cancer biology. Abnormal MOK expression or activity can contribute to uncontrolled cell growth and division, a hallmark of cancer.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580, a p38 MAP kinase inhibitor, can influence signaling pathways, potentially impacting MOK activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, can affect various cellular signaling pathways, potentially influencing MOK activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, leading to increased cAMP levels, which may indirectly influence MOK. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
TSA, a histone deacetylase inhibitor, can modulate chromatin structure and gene expression, potentially affecting MOK activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a compound in turmeric, affects multiple signaling pathways and might have an indirect impact on MOK. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, found in grapes, can modulate various cellular processes potentially influencing MOK activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride, known to inhibit GSK-3β and modulate the Wnt pathway, could have an indirect effect on MOK. | ||||||