Date published: 2025-9-9

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MNSF-β Inhibitors

MNSF-β Inhibitors refers to a specialized category of chemical compounds designed to interact with and modulate the activity of MNSF-β, also known as Monocyte-derived neutrophil chemotactic factor (MDNCF) or Interleukin-16 (IL-16). IL-16 is a multifunctional cytokine that plays a role in immune system regulation and inflammation. It is produced by various immune cells, including CD4+ T lymphocytes, mast cells, and dendritic cells. IL-16 has been implicated in immune cell activation, chemotaxis, and the regulation of inflammatory responses. Inhibitors of MNSF-β are developed to interact with this specific cytokine, potentially influencing its biological activities, cellular signaling pathways, or interactions with immune cells.

Structurally, MNSF-β inhibitors are designed to engage specific regions or binding sites on the IL-16 molecule. This interaction can disrupt the normal functioning of IL-16, potentially altering its ability to act as a chemotactic factor for immune cells or to modulate immune responses. The mechanisms by which MNSF-β inhibitors exert their effects can vary, but their primary objective is to serve as valuable research tools for scientists studying the roles of IL-16 in the immune system and inflammation. Investigating the biochemical and functional aspects of IL-16 and its modulation by inhibitors can contribute to a deeper understanding of immune cell behavior, chemotaxis, and the broader field of immunology, ultimately offering insights into the intricate mechanisms governing immune responses and inflammatory processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$62.00
$90.00
$299.00
$475.00
$1015.00
$2099.00
69
(5)

As an immunosuppressant, Cyclosporine A affects T-cell activity and could indirectly modulate MNSF-β expression in immune responses.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

This glucocorticoid can influence immune cell function and gene expression, potentially impacting MNSF-β levels.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

By inhibiting inosine monophosphate dehydrogenase, it affects purine synthesis in lymphocytes, potentially influencing MNSF-β expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Affects mTOR signaling and thus can modulate immune responses, potentially impacting MNSF-β levels.

Azathioprine

446-86-6sc-210853D
sc-210853
sc-210853A
sc-210853B
sc-210853C
500 mg
1 g
2 g
5 g
10 g
$199.00
$173.00
$342.00
$495.00
$690.00
1
(1)

An immunosuppressive, it affects purine synthesis which might indirectly modulate MNSF-β expression.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

As an immunosuppressant and antifolate, Methotrexate can impact cellular proliferation and potentially MNSF-β expression.

hydroxychloroquine

118-42-3sc-507426
5 g
$56.00
1
(0)

Used in autoimmune diseases, this compound might modulate immune cell function and possibly MNSF-β levels.

FK-506

104987-11-3sc-24649
sc-24649A
5 mg
10 mg
$76.00
$148.00
9
(1)

Immunosuppressant that inhibits T-cell activation, potentially influencing MNSF-β expression.

6-Mercaptopurine

50-44-2sc-361087
sc-361087A
50 mg
100 mg
$71.00
$102.00
(0)

Influences purine metabolism and can modulate immune responses, potentially affecting MNSF-β expression.

Leflunomide

75706-12-6sc-202209
sc-202209A
10 mg
50 mg
$20.00
$81.00
5
(1)

Immunosuppressive drug that might influence cellular processes related to MNSF-β expression.