MNSF-β Inhibitors refers to a specialized category of chemical compounds designed to interact with and modulate the activity of MNSF-β, also known as Monocyte-derived neutrophil chemotactic factor (MDNCF) or Interleukin-16 (IL-16). IL-16 is a multifunctional cytokine that plays a role in immune system regulation and inflammation. It is produced by various immune cells, including CD4+ T lymphocytes, mast cells, and dendritic cells. IL-16 has been implicated in immune cell activation, chemotaxis, and the regulation of inflammatory responses. Inhibitors of MNSF-β are developed to interact with this specific cytokine, potentially influencing its biological activities, cellular signaling pathways, or interactions with immune cells.
Structurally, MNSF-β inhibitors are designed to engage specific regions or binding sites on the IL-16 molecule. This interaction can disrupt the normal functioning of IL-16, potentially altering its ability to act as a chemotactic factor for immune cells or to modulate immune responses. The mechanisms by which MNSF-β inhibitors exert their effects can vary, but their primary objective is to serve as valuable research tools for scientists studying the roles of IL-16 in the immune system and inflammation. Investigating the biochemical and functional aspects of IL-16 and its modulation by inhibitors can contribute to a deeper understanding of immune cell behavior, chemotaxis, and the broader field of immunology, ultimately offering insights into the intricate mechanisms governing immune responses and inflammatory processes.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
As an immunosuppressant, Cyclosporine A affects T-cell activity and could indirectly modulate MNSF-β expression in immune responses. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
This glucocorticoid can influence immune cell function and gene expression, potentially impacting MNSF-β levels. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
By inhibiting inosine monophosphate dehydrogenase, it affects purine synthesis in lymphocytes, potentially influencing MNSF-β expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Affects mTOR signaling and thus can modulate immune responses, potentially impacting MNSF-β levels. | ||||||
Azathioprine | 446-86-6 | sc-210853D sc-210853 sc-210853A sc-210853B sc-210853C | 500 mg 1 g 2 g 5 g 10 g | $199.00 $173.00 $342.00 $495.00 $690.00 | 1 | |
An immunosuppressive, it affects purine synthesis which might indirectly modulate MNSF-β expression. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
As an immunosuppressant and antifolate, Methotrexate can impact cellular proliferation and potentially MNSF-β expression. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $56.00 | 1 | |
Used in autoimmune diseases, this compound might modulate immune cell function and possibly MNSF-β levels. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $76.00 $148.00 | 9 | |
Immunosuppressant that inhibits T-cell activation, potentially influencing MNSF-β expression. | ||||||
6-Mercaptopurine | 50-44-2 | sc-361087 sc-361087A | 50 mg 100 mg | $71.00 $102.00 | ||
Influences purine metabolism and can modulate immune responses, potentially affecting MNSF-β expression. | ||||||
Leflunomide | 75706-12-6 | sc-202209 sc-202209A | 10 mg 50 mg | $20.00 $81.00 | 5 | |
Immunosuppressive drug that might influence cellular processes related to MNSF-β expression. |