MLF2 Activators
MLF2, or Myeloid Leukemia Factor 2, is a protein encoded by the MLF2 gene in humans. It is part of the myeloid leukemia factor family, known for their involvement in hematopoiesis and their role in leukemia.The precise biological function of MLF2 is not fully understood, but it is believed to play a role in the regulation of cell proliferation and differentiation, particularly within the hematopoietic system. This system is responsible for the production of blood cells, and the proper regulation of these processes is crucial for maintaining healthy blood cell levels and function.
MLF2 is expressed in various tissues, including those involved in the immune system, suggesting a broader role beyond just hematopoiesis. The protein may be involved in cellular signaling pathways that regulate immune responses or other aspects of cell function.In the context of leukemia, MLF2 has been a subject of interest due to its involvement in the pathogenesis of the disease. Some studies suggest that alterations in the expression or function of MLF2, as well as other members of the myeloid leukemia factor family, could contribute to the development or progression of leukemia. This makes it a target for research in cancer biology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
All-trans Retinoic Acid is used in differentiation therapy, especially in acute promyelocytic leukemia, and could indirectly affect MLF2-related pathways. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a glucocorticoid, is involved in hematopoietic processes and might influence MLF2 function. | ||||||
Lenalidomide | 191732-72-6 | sc-218656 sc-218656A sc-218656B | 10 mg 100 mg 1 g | $50.00 $374.00 $2071.00 | 18 | |
Lenalidomide affects various signaling pathways in hematopoietic cells and may have indirect effects on MLF2. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, a key regulator of cell growth and proliferation, potentially influencing MLF2 activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine, a DNA methyltransferase inhibitor, is used in myelodysplastic syndromes and could impact MLF2-related pathways. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Decitabine, similar to 5-Azacytidine, affects DNA methylation and might influence MLF2 function. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
JQ1, a BET bromodomain inhibitor, influences transcriptional regulation and may indirectly affect MLF2. | ||||||
Imatinib mesylate | 220127-57-1 | sc-202180 sc-202180A | 25 mg 100 mg | $45.00 $111.00 | 61 | |
Imatinib, a tyrosine kinase inhibitor, can affect signaling pathways relevant to MLF2 in hematopoietic cells. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $111.00 $357.00 | 8 | |
Thalidomide affects several signaling pathways and has immunomodulatory effects, potentially influencing MLF2. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
Hydroxyurea is used in myeloproliferative disorders and could impact pathways involving MLF2. | ||||||