Chemical activators of the protein Mec3 play a crucial role in modulating the function of this protein, thereby influencing the biological pathways it is involved in. Mec3 activators are a class of compounds that can enhance the activity of Mec3, a protein implicated in several critical cellular processes. These activators can be small molecules, peptides, or other biochemical agents designed to interact specifically with Mec3, leading to an increase in its activity. The interaction between Mec3 activators and the protein can occur through various mechanisms, such as altering the protein's conformation to a more active state, stabilizing the protein in its active form, or enhancing its affinity for substrates or other interacting proteins. This interaction is highly specific, ensuring that the activation of Mec3 is precise and effective, thereby facilitating the desired biological outcomes.
Mec3 activators are developed through comprehensive research and development processes that involve the identification of the protein's active sites, understanding the molecular structure of Mec3, and elucidating the mechanisms through which it exerts its biological effects. The development of these activators requires sophisticated techniques, including high-throughput screening, molecular docking, and structure-activity relationship (SAR) studies, to identify compounds that can interact with Mec3 in a manner that enhances its activity. Once potential activators are identified, they undergo rigorous testing in biochemical assays to confirm their ability to activate Mec3, followed by cellular assays to assess their efficacy in a biological context. The ultimate goal is to achieve selective activation of Mec3, thereby modulating the pathways in which it is involved to achieve desired research outcomes. Through these methods, researchers can develop a deeper understanding of Mec3's role in cellular processes and harness the potential of its activators for various applications in biotechnology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclophosphamide | 50-18-0 | sc-361165 sc-361165A sc-361165B sc-361165C | 50 mg 100 mg 500 mg 1 g | $76.00 $143.00 $469.00 $775.00 | 18 | |
May cause DNA crosslinks and damage, possibly leading to an upregulation of DNA repair proteins. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Can insert into DNA, causing damage and potentially inducing DNA repair mechanisms. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Mimics folate and can disrupt DNA synthesis, potentially leading to DNA damage and repair activation. | ||||||
Bleomycin Sulfate | 9041-93-4 | sc-200134 sc-200134A sc-200134B sc-200134C | 10 mg 50 mg 100 mg 500 mg | $206.00 $612.00 $1020.00 $2856.00 | 38 | |
Induces double-strand DNA breaks similar to those caused by ionizing radiation, potentially activating DNA repair pathways. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
Generates reactive oxygen species leading to DNA damage, which may upregulate DNA repair proteins. | ||||||
Psoralen | 66-97-7 | sc-205965 sc-205965A | 25 mg 100 mg | $101.00 $315.00 | 1 | |
Interacts with DNA in the presence of UV light, forming crosslinks and potentially inducing DNA repair pathways. | ||||||
ATM Kinase Inhibitor | 587871-26-9 | sc-202963 | 2 mg | $108.00 | 28 | |
Blocking ATM kinase can impair the DNA damage response, potentially leading to upregulation of DNA repair proteins. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
Promotes heat shock protein expression, which can be part of the cellular response to DNA damage. | ||||||