Psoralen (CAS 66-97-7)
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Psoralen, a naturally occurring compound present in various plants such as citrus fruits, parsnips, and figs. It has become a subject of scientific interest, prompting research into its diverse applications. Research on psoralen has unveiled its array of biochemical and physiological effects, leading to investigations into its potential applications in scientific fields. Psoralen exhibits anti-inflammatory, antimicrobial, and antioxidant properties. Psoralen involves the activation of various pathways within the body. It is known to interact with DNA, potentially hindering the activity of enzymes involved in DNA replication and repair. psoralen activates specific proteins in the body, leading to the production of anti-inflammatory and antioxidant compounds. Additionally, it is thought to interact with cell surface receptors, influencing cell signaling pathways.
Psoralen (CAS 66-97-7) References
- Probing DNA structure with psoralen in vitro. | Ussery, DW., et al. 1992. Methods Enzymol. 212: 242-62. PMID: 1325599
- Psoralen photocrosslinking, a tool to study the chromatin structure of RNA polymerase I--transcribed ribosomal genes. | Toussaint, M., et al. 2005. Biochem Cell Biol. 83: 449-59. PMID: 16094448
- Psoralen-induced DNA adducts are substrates for the base excision repair pathway in human cells. | Couvé-Privat, S., et al. 2007. Nucleic Acids Res. 35: 5672-82. PMID: 17715144
- Site-directed gene mutation at mixed sequence targets by psoralen-conjugated pseudo-complementary peptide nucleic acids. | Kim, KH., et al. 2007. Nucleic Acids Res. 35: 7604-13. PMID: 17977869
- Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry. | Cimino, GD., et al. 1985. Annu Rev Biochem. 54: 1151-93. PMID: 2411210
- Electron microscopic identification of supercoiled regions in complex DNA structures. | Inman, RB. and Schnös, M. 1987. J Mol Biol. 193: 377-84. PMID: 2955121
- Psoralen Derivatives: Recent Advances of Synthetic Strategy and Pharmacological Properties. | Jamalis, J., et al. 2020. Antiinflamm Antiallergy Agents Med Chem. 19: 222-239. PMID: 31241020
- The Science and (Lost) Art of Psoralen Plus UVA Phototherapy. | Richard, EG. 2020. Dermatol Clin. 38: 11-23. PMID: 31753184
- Psoralen: A Biologically Important Coumarin with Emerging Applications. | Thakur, A., et al. 2020. Mini Rev Med Chem. 20: 1838-1845. PMID: 32348216
- Psoralen-Induced Phytophotodermatitis. | Ellis, CR. and Elston, DM. Dermatitis. 32: 140-143. PMID: 33273237
- Psoralen induces liver injuries through endoplasmic reticulum stress signaling in female mice. | Yu, R., et al. 2022. Drug Chem Toxicol. 45: 1818-1824. PMID: 33557643
- Psoralen induces hepatotoxicity by covalently binding to glutathione-S-transferases and the hepatic cytochrome P450. | Jiang, M., et al. 2022. Phytomedicine. 104: 154165. PMID: 35792449
- Psoralen downregulates osteoarthritis chondrocyte inflammation via an estrogen-like effect and attenuates osteoarthritis. | Huang, K., et al. 2022. Aging (Albany NY). 14: 6716-6726. PMID: 36036756
- Psoralen phototoxicity: correlation with serum and epidermal 8-methoxypsoralen and 5-methoxypsoralen in the guinea pig. | Kornhauser, A., et al. 1982. Science. 217: 733-5. PMID: 7100920
- DNA interstrand cross-links induced by psoralen are not repaired in mammalian mitochondria. | Cullinane, C. and Bohr, VA. 1998. Cancer Res. 58: 1400-4. PMID: 9537239
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Psoralen, 25 mg | sc-205965 | 25 mg | $103.00 | |||
Psoralen, 100 mg | sc-205965A | 100 mg | $321.00 |