MDH1B Activators
The potential activators for Malate Dehydrogenase 1B (MDH1B) primarily target aspects of mitochondrial function and cellular metabolism, thereby indirectly influencing MDH1B activity. These activators include compounds that modulate mitochondrial efficiency and redox balance. NAD+ precursors, such as nicotinamide riboside, can enhance mitochondrial function and the overall redox state of the cell, potentially impacting the activity of MDH1B, which is involved in the malate-aspartate shuttle. Alpha-lipoic acid and Coenzyme Q10 are known to support mitochondrial function. Alpha-lipoic acid acts as an antioxidant, while Coenzyme Q10 is a key component in the electron transport chain. Both of these could indirectly support the function of MDH1B within the mitochondria.
Similarly, metformin and berberine, which are known to modulate cellular metabolism and mitochondrial function, might have indirect effects on MDH1B. Sulforaphane and curcumin, with their roles in modulating cellular antioxidant responses and mitochondrial function, could also impact MDH1B. Epigallocatechin gallate (EGCG) affects mitochondrial health and cellular metabolism, which may have downstream effects on MDH1B's function. Furthermore, compounds involved in energy metabolism such as creatine and carnitine might indirectly influence MDH1B. Creatine is involved in ATP regeneration, while carnitine facilitates the transport of fatty acids into mitochondria for beta-oxidation, supporting overall mitochondrial function and potentially MDH1B activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
An antioxidant that supports mitochondrial function and redox balance, which might affect MDH1B. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Involved in the electron transport chain, it could support mitochondrial processes related to MDH1B. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Influences metabolic pathways and mitochondrial function, potentially impacting MDH1B. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Can modulate cellular antioxidant responses and mitochondrial function, possibly affecting MDH1B. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Affects various metabolic pathways and mitochondrial function, potentially modulating MDH1B. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Influences mitochondrial health and cellular metabolism, potentially impacting MDH1B. | ||||||
Creatine, anhydrous | 57-00-1 | sc-214774 sc-214774A | 10 mg 50 g | $28.00 $79.00 | 2 | |
Known to impact energy metabolism, which may indirectly affect MDH1B. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $34.00 $79.00 $179.00 | 3 | |
Essential for fatty acid transport into mitochondria, potentially supporting MDH1B activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
As an mTOR inhibitor, it might influence metabolic processes, potentially impacting MDH1B. | ||||||