MDH1B Inhibitors
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
K252c | 85753-43-1 | sc-24011 sc-24011A | 1 mg 5 mg | $87.00 $374.00 | 3 | |
K252c is a selective inhibitor of MDH1B, exhibiting unique binding dynamics that disrupt enzyme-substrate interactions. Its structural conformation allows for precise fit within the active site, leading to altered reaction kinetics and modulation of metabolic pathways. The compound's hydrophobic regions facilitate interactions with lipid membranes, enhancing its bioavailability and stability. K252c's distinct molecular interactions contribute to its specificity, making it a valuable tool for studying MDH1B-related processes. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $108.00 $780.00 | 3 | |
Sodium (meta)arsenite can inhibit several enzymes involved in cellular respiration, potentially affecting mitochondrial function and indirectly MDH1B. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Rotenone inhibits mitochondrial complex I, impacting electron transport and potentially the redox state, which could influence MDH1B activity. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
Antimycin A inhibits mitochondrial complex III, affecting electron transport and potentially influencing the NAD⁺/NADH balance and MDH1B function. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Oligomycin inhibits ATP synthase (complex V), impacting ATP production and potentially influencing mitochondrial metabolism including MDH1B activity. | ||||||
Allopurinol | 315-30-0 | sc-207272 | 25 g | $131.00 | ||
Allopurinol affects purine metabolism and can influence cellular NAD⁺/NADH levels, potentially impacting MDH1B function. | ||||||
Phenformin Hydrochloride | 834-28-6 | sc-219590 | 10 g | $119.00 | 4 | |
Phenformin, a biguanide, can inhibit mitochondrial complex I, potentially affecting MDH1B by altering mitochondrial metabolism. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
2-Deoxy-D-glucose inhibits glycolysis, leading to altered cellular energy states, which might indirectly affect MDH1B activity. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin can influence mitochondrial function and has been shown to affect complex I activity, potentially impacting MDH1B. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR is an activator of AMP-activated protein kinase (AMPK) and affects cellular energy metabolism, potentially influencing MDH1B. | ||||||