MBOAT5, a key enzyme in the acylation of lysophospholipids, is influenced by various fatty acids and related compounds that serve as substrates or modulators of its enzymatic activity. The presence of fatty acids such as Oleic Acid, Palmitic Acid, Linoleic Acid, and Arachidonic Acid (20:4, n-6) directly enhances MBOAT5's activity. These fatty acids are crucial for MBOAT5's role in incorporating them into phospholipids, a process vital for membrane biosynthesis and remodeling. This enzymatic activity is essential for maintaining and altering cellular membrane composition, impacting cell signaling, membrane fluidity, and overall cellular function. The interaction of MBOAT5 with these substrates is fundamental to the synthesis of bioactive lipids, influencing a variety of cellular signaling pathways and membrane dynamics.
Moreover, the availability of phospholipids like L-α-Lecithin, Egg Yolk, Highly Purified and Lysophosphatidylcholine, as well as components like Choline and Ethanolamine, indirectly affects MBOAT5's functional role in lipid metabolism. MBOAT5's modification of these phospholipids is critical for determining membrane properties and cell signaling processes. Additionally, the presence of sphingolipid components like D-erythro-Sphingosine can indirectly modulate MBOAT5 activity, further influencing lipid metabolism and membrane composition. Polyunsaturated fatty acids such as Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3), Eicosapentaenoic Acid (EPA), and α-Linolenic Acid also serve as substrates for MBOAT5, playing a significant role in the enzyme's function in neural tissues and inflammatory responses. The incorporation of these fatty acids into membrane phospholipids by MBOAT5 is crucial for maintaining membrane fluidity, functionality, and the mediation of various cellular processes. Collectively, these compounds, through their roles as substrates or modulators, synergistically enhance the functional activity of MBOAT5, underscoring its pivotal role in lipid metabolism and membrane physiology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
As a monounsaturated fatty acid, Oleic Acid can serve as a substrate for MBOAT5, which is involved in the acylation of lysophospholipids. This interaction potentially enhances the enzymatic activity of MBOAT5 in incorporating fatty acids into phospholipids, which is crucial for membrane biosynthesis and remodeling. | ||||||
Palmitic Acid | 57-10-3 | sc-203175 sc-203175A | 25 g 100 g | $112.00 $280.00 | 2 | |
A saturated fatty acid that can act as a substrate for MBOAT5. The availability of Palmitic Acid can increase MBOAT5's activity in the acylation of lysophospholipids, a process important for the maintenance and alteration of cellular membrane composition. | ||||||
Linoleic Acid | 60-33-3 | sc-200788 sc-200788A sc-200788B sc-200788C | 100 mg 1 g 5 g 25 g | $33.00 $63.00 $163.00 $275.00 | 4 | |
An essential polyunsaturated fatty acid, Linoleic Acid can be utilized by MBOAT5 as a substrate for the synthesis of phospholipids. The presence of Linoleic Acid can enhance the function of MBOAT5 in membrane lipid remodeling, which is vital for various cellular functions including cell signaling and membrane fluidity. | ||||||
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $90.00 $235.00 $4243.00 | 9 | |
A polyunsaturated fatty acid that can serve as a substrate for MBOAT5. The enzymatic activity of MBOAT5 in incorporating Arachidonic Acid into phospholipids is critical for the production of bioactive lipids and can impact cellular signaling pathways and membrane dynamics. | ||||||
L-α-Lecithin, Egg Yolk, Highly Purified | 8002-43-5 | sc-203096 | 250 mg | $78.00 | ||
As a major component of biological membranes, L-α-Lecithin, Egg Yolk, Highly Purified availability can influence MBOAT5 activity. MBOAT5 modifies L-α-Lecithin, Egg Yolk, Highly Purified by incorporating various fatty acids, impacting membrane composition and cell signaling processes. | ||||||
Choline chloride | 67-48-1 | sc-207430 sc-207430A sc-207430B | 10 mg 5 g 50 g | $32.00 $36.00 $51.00 | 1 | |
As a component of phosphatidylcholine, Choline availability can indirectly affect MBOAT5 activity. MBOAT5's role in modifying phosphatidylcholine and related lipids can be influenced by the availability of Choline, impacting lipid metabolism and membrane composition. | ||||||
Ethanolamine | 141-43-5 | sc-203042 sc-203042A sc-203042B | 25 ml 500 ml 2.5 L | $21.00 $55.00 $200.00 | 1 | |
Involved in the synthesis of phosphatidylethanolamine, Ethanolamine can indirectly influence MBOAT5 activity, as MBOAT5 modifies phospholipids including phosphatidylethanolamine, affecting membrane fluidity and function. | ||||||
D-erythro-Sphingosine | 123-78-4 | sc-3546 sc-3546A sc-3546B sc-3546C sc-3546D sc-3546E | 10 mg 25 mg 100 mg 1 g 5 g 10 g | $88.00 $190.00 $500.00 $2400.00 $9200.00 $15000.00 | 2 | |
As a component of sphingolipids, D-erythro-Sphingosine can indirectly influence the activity of MBOAT5. MBOAT5's involvement in lipid metabolism and membrane composition can be modulated by the presence of sphingolipids and their components. | ||||||
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $92.00 $206.00 $1744.00 $7864.00 $16330.00 | 11 | |
A polyunsaturated fatty acid that serves as a substrate for MBOAT5. The incorporation of DHA by MBOAT5 into phospholipids is important for membrane fluidity and function, particularly in neural tissues, and can impact cellular signaling and membrane dynamics. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $102.00 $423.00 | ||
A polyunsaturated fatty acid utilized by MBOAT5. EPA incorporation into phospholipids by MBOAT5 affects membrane properties and can have implications for inflammatory responses and cell signaling. | ||||||