Date published: 2025-12-9

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MAS1 Activators

MAS1 Activators constitute a specialized category of chemical compounds designed to modulate the activity of the MAS1 receptor. The MAS1 receptor, also known as MAS-related G protein-coupled receptor member D (MRGD), is a member of the G protein-coupled receptor (GPCR) family. GPCRs are a diverse group of cell surface receptors that play a fundamental role in transmitting extracellular signals to intracellular pathways, thereby regulating various physiological processes. MAS1, in particular, is of interest due to its association with the renin-angiotensin system and its roles in cardiovascular and other physiological systems.

MAS1 Activators are compounds engineered to interact with the MAS1 receptor and influence its signaling pathways. These activators can either enhance or inhibit the receptor's activation, depending on their chemical structure and mode of action. By targeting MAS1, these compounds may impact downstream cellular responses, making them valuable tools for researchers exploring the functions of MAS1 in various biological contexts. Although the precise physiological roles and functions of MAS1 are still being elucidated, it is believed to be involved in processes such as blood pressure regulation, vasodilation, and anti-inflammatory responses. Therefore, the study of MAS1 Activators contributes to a deeper understanding of GPCR signaling and its relevance in diverse physiological processes. Researchers continue to investigate the mechanisms of MAS1 activation and its implications in cellular and systemic responses, shedding light on the complex network of GPCR-mediated signaling pathways.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Angiotensin fragment 1-7 acetate salt

51833-78-4sc-319824
1 mg
$82.00
1
(1)

Directly activates MAS1 by binding to its active site, promoting vasodilation and anti-inflammatory effects.

PD 123319 ditrifluoroacetate

130663-39-7sc-204835
sc-204835A
10 mg
50 mg
$209.00
$826.00
5
(1)

Although primarily an AT2 receptor antagonist, it can indirectly influence MAS1 signaling pathways.

Telmisartan

144701-48-4sc-204907
sc-204907A
50 mg
100 mg
$71.00
$92.00
8
(1)

Known as an angiotensin II receptor blocker, it may also have indirect effects on MAS1 activation.

Losartan

114798-26-4sc-353662
100 mg
$127.00
18
(1)

Primarily an AT1 antagonist, it can modulate MAS1 activity indirectly through RAS pathway interactions.