MAS1 Activators constitute a specialized category of chemical compounds designed to modulate the activity of the MAS1 receptor. The MAS1 receptor, also known as MAS-related G protein-coupled receptor member D (MRGD), is a member of the G protein-coupled receptor (GPCR) family. GPCRs are a diverse group of cell surface receptors that play a fundamental role in transmitting extracellular signals to intracellular pathways, thereby regulating various physiological processes. MAS1, in particular, is of interest due to its association with the renin-angiotensin system and its roles in cardiovascular and other physiological systems.
MAS1 Activators are compounds engineered to interact with the MAS1 receptor and influence its signaling pathways. These activators can either enhance or inhibit the receptor's activation, depending on their chemical structure and mode of action. By targeting MAS1, these compounds may impact downstream cellular responses, making them valuable tools for researchers exploring the functions of MAS1 in various biological contexts. Although the precise physiological roles and functions of MAS1 are still being elucidated, it is believed to be involved in processes such as blood pressure regulation, vasodilation, and anti-inflammatory responses. Therefore, the study of MAS1 Activators contributes to a deeper understanding of GPCR signaling and its relevance in diverse physiological processes. Researchers continue to investigate the mechanisms of MAS1 activation and its implications in cellular and systemic responses, shedding light on the complex network of GPCR-mediated signaling pathways.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Angiotensin fragment 1-7 acetate salt | 51833-78-4 | sc-319824 | 1 mg | $82.00 | 1 | |
Directly activates MAS1 by binding to its active site, promoting vasodilation and anti-inflammatory effects. | ||||||
PD 123319 ditrifluoroacetate | 130663-39-7 | sc-204835 sc-204835A | 10 mg 50 mg | $209.00 $826.00 | 5 | |
Although primarily an AT2 receptor antagonist, it can indirectly influence MAS1 signaling pathways. | ||||||
Telmisartan | 144701-48-4 | sc-204907 sc-204907A | 50 mg 100 mg | $71.00 $92.00 | 8 | |
Known as an angiotensin II receptor blocker, it may also have indirect effects on MAS1 activation. | ||||||
Losartan | 114798-26-4 | sc-353662 | 100 mg | $127.00 | 18 | |
Primarily an AT1 antagonist, it can modulate MAS1 activity indirectly through RAS pathway interactions. | ||||||