Molecular structure of Angiotensin fragment 1-7 acetate salt, CAS Number: 51833-78-4
Angiotensin fragment 1-7 acetate salt (CAS 51833-78-4)
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Application:
Angiotensin fragment 1-7 acetate salt is an angiotensin I metabolite that is an AT2 receptor activator
CAS Number:
51833-78-4
Purity:
≥90%
Molecular Weight:
899.00(free base)
Molecular Formula:
C41H62N12O11•XC2H4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Angiotensin fragment 1-7 acetate salt refers to a specific segment of the angiotensin peptide chain, which includes amino acids 1 through 7, with an acetate salt form to enhance its stability and solubility. This fragment is a derivative of the angiotensin peptide. While the full-length angiotensin molecule has well-documented effects, this shorter fragment is of interest for its distinct biochemical properties and potential physiological effects that diverge from those of the longer chain. Angiotensin fragment 1-7 acetate salt is utilized for its potential to provide insights into the broader angiotensin system. This fragment can act on different receptors and pathways compared to the full-length peptide.
Angiotensin fragment 1-7 acetate salt (CAS 51833-78-4) References
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- Anti-inflammatory action of angiotensin 1-7 in experimental colitis may be mediated through modulation of serum cytokines/chemokines and immune cell functions. | Khajah, MA., et al. 2017. Dev Comp Immunol. 74: 200-208. PMID: 28487234
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- Central angiotensin-(1-7) attenuates systemic inflammation via activation of sympathetic signaling in endotoxemic rats. | Passaglia, P., et al. 2020. Brain Behav Immun. 88: 606-618. PMID: 32335195
- SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45- Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein Activates the Nlrp3 Inflammasome. | Ratajczak, MZ., et al. 2021. Stem Cell Rev Rep. 17: 266-277. PMID: 32691370
- SARS-CoV-2 Spike Protein Disrupts Blood-Brain Barrier Integrity via RhoA Activation. | DeOre, BJ., et al. 2021. J Neuroimmune Pharmacol. 16: 722-728. PMID: 34687399
- Angiotensin 1-7 mitigates rhabdomyolysis induced renal injury in rats via modulation of TLR-4/NF-kB/iNOS and Nrf-2/heme‑oxygenase-1 signaling pathways. | Abdel-Hakeem, EA., et al. 2022. Life Sci. 303: 120678. PMID: 35654118
- Dysregulated ACE/Ang II/Ang1-7 signaling provokes cardiovascular and inflammatory sequelae of endotoxemia in weaning preeclamptic rats. | Abuiessa, SA., et al. 2022. Eur J Pharmacol. 936: 175344. PMID: 36270538
Activator of:
AT1, AT2, Biglycan, Dear, MAS1, and MRGD.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Angiotensin fragment 1-7 acetate salt, 1 mg | sc-319824 | 1 mg | $82.00 |