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Telmisartan is an angiotensin II receptor blocker (ARB) that has high affinity for the angiotensin II receptor type 1 (AT1). Telmisartan interferes with the binding of angiotensin II to AT1 receptors in vascular smooth muscle and thus inhibits the vasoconstricting action of angiotensin II. Additionally, telmisartan is a selective modulator of peroxisome proliferator-activated receptor gamma (PPARγ), an essential regulator of insulin and glucose metabolism. Therefore, telmisartan is useful for studying hypertension.
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See how others have used Telmisartan. Click on the entry to view the PubMed entry .
PMID: # 27693991 Görgens, C. et al. 2016. Journal of pharmaceutical and biomedical analysis. 131: 482-496.
PMID: # 26420482 Zhang, H. et al. 2015. J. Biol. Chem. 290: 29127-39.
PMID: # 24301614 Kumai, Y. et al. 2014. The Journal of endocrinology. 220: 195-205.
PMID: # 20362079 Ma, L. et al. 2010. Bone. 47: 5-11.
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