MANSC4 Activators
MANSC4, predicted to be an integral component of the membrane, is involved in crucial cellular processes related to membrane dynamics and localization. Its activation is intricately linked to various chemical regulators that modulate membrane-associated pathways, influencing the expression and membrane integration of MANSC4. The activation of MANSC4 is facilitated by chemicals such as Brefeldin A, Forskolin, and Chlorpromazine, impacting Golgi dynamics, cAMP-dependent pathways, and calmodulin signaling, respectively. Agents like Amphotericin B and Wortmannin influence membrane integrity and PI3K-dependent pathways, indirectly promoting MANSC4 activation. The histamine H1 receptor antagonist Terfenadine and actin polymerization inhibitor Latrunculin A disrupt histamine signaling and actin cytoskeleton, triggering cellular responses that enhance MANSC4 expression and membrane integration.
Additionally, Cholesterol and Blebbistatin influence membrane composition and myosin II-dependent processes, respectively, contributing to MANSC4 activation. Chemicals like Dynasore, EIPA, and Nystatin disrupt membrane trafficking, Na⁺/H⁺ exchanger activity, and membrane integrity, respectively, indirectly enhancing the expression and membrane integration of MANSC4. In summary, MANSC4 activation involves a complex interplay of chemical regulators that modulate various membrane-associated processes. This understanding sheds light on the mechanisms by which MANSC4 contributes to cellular functions, emphasizing its role as an integral component of the membrane involved in crucial cellular processes.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Golgi disruptor impacting MANSC4 localization. Brefeldin A indirectly activates MANSC4 by affecting membrane trafficking, triggering cellular responses that enhance the expression and membrane integration of MANSC4. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Calmodulin antagonist influencing membrane-associated processes. Chlorpromazine indirectly activates MANSC4 by disrupting calmodulin-dependent signaling, triggering cellular responses that enhance MANSC4 expression and membrane integration. | ||||||
Amphotericin B | 1397-89-3 | sc-202462 sc-202462A sc-202462B | 100 mg 500 mg 1 g | $70.00 $142.00 $223.00 | 10 | |
Antifungal agent impacting membrane integrity. Amphotericin B indirectly activates MANSC4 by influencing membrane composition and stability, triggering cellular responses that enhance the expression and membrane integration of MANSC4. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Phosphoinositide 3-kinase (PI3K) inhibitor influencing membrane dynamics. Wortmannin indirectly activates MANSC4 by modulating PI3K-dependent pathways, impacting membrane-associated processes that lead to enhanced MANSC4 expression. | ||||||
Terfenadine | 50679-08-8 | sc-208421A sc-208421B sc-208421 | 500 mg 1 g 5 g | $44.00 $71.00 $120.00 | ||
Histamine H1 receptor antagonist influencing membrane-associated processes. Terfenadine indirectly activates MANSC4 by blocking histamine signaling, triggering cellular responses that enhance MANSC4 expression and membrane integration. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Actin polymerization inhibitor impacting membrane dynamics. Latrunculin A indirectly activates MANSC4 by disrupting actin cytoskeleton, triggering cellular responses that enhance the expression and membrane integration of MANSC4. | ||||||
Cholesterol | 57-88-5 | sc-202539C sc-202539E sc-202539A sc-202539B sc-202539D sc-202539 | 5 g 5 kg 100 g 250 g 1 kg 25 g | $27.00 $2809.00 $129.00 $210.00 $583.00 $88.00 | 11 | |
Membrane component impacting MANSC4 localization. Cholesterol indirectly activates MANSC4 by influencing membrane composition, triggering cellular responses that enhance the expression and membrane integration of MANSC4. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Myosin II inhibitor influencing membrane dynamics. Blebbistatin indirectly activates MANSC4 by disrupting myosin II-dependent processes, triggering cellular responses that enhance the expression and membrane integration of MANSC4. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Dynamin inhibitor impacting membrane trafficking. Dynasore indirectly activates MANSC4 by disrupting dynamin-dependent processes, triggering cellular responses that enhance the expression and membrane integration of MANSC4. | ||||||
5-(N-Ethyl-N-isopropyl)-Amiloride | 1154-25-2 | sc-202458 | 5 mg | $104.00 | 20 | |
Na⁺/H⁺ exchanger inhibitor influencing membrane dynamics. EIPA indirectly activates MANSC4 by disrupting Na⁺/H⁺ exchanger activity, triggering cellular responses that enhance the expression and membrane integration of MANSC4. | ||||||