MAGI-2 Activators
MAGI-2 activators, in this context, are chemical compounds that indirectly influence the activity of the MAGI-2 protein. They represent a diverse group of molecules, including phospholipids, protein synthesis inhibitors, protein phosphatase inhibitors, kinase inhibitors, ion channel blockers, and disruptors of cellular structure and calcium homeostasis.
The mechanisms by which these compounds may affect MAGI-2 are centered around their ability to modulate various cellular processes that MAGI-2 is known to be involved in. For example, phosphorylation levels, cell adhesion, synapse organization, calcium homeostasis, and apoptosis signaling are all cellular processes that can be influenced by these compounds and are also processes in which MAGI-2 plays a role. The specific effect of each compound on MAGI-2 may depend on numerous factors, including the concentration of the compound, the cell type, and the current physiological or pathophysiological state of the cell. Therefore, the mechanisms by which these compounds influence MAGI-2 are complex and multifaceted.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Phosphatidyl-L-serine | 51446-62-9 | sc-507548 | 10 g | $46.00 | ||
This lipid molecule is involved in the regulation of apoptosis, a process in which MAGI-2 is implicated. Increased levels of phosphatidylserine may result in changes to apoptosis signaling, which could alter the function of MAGI-2. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
This disrupts microtubules and affects cellular structure. As MAGI-2 is involved in cell adhesion and synapse organization, changes to cellular structure can influence its activity. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
This inhibitor of protein phosphatases can increase phosphorylation levels in the cell. As MAGI-2 is a protein that can be phosphorylated, this could indirectly activate it. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
This activates adenylate cyclase, increasing cAMP levels. As cAMP is a second messenger in multiple signaling pathways, this could indirectly influence MAGI-2. | ||||||
Picrotoxin | 124-87-8 | sc-202765 sc-202765A sc-202765B | 1 g 5 g 25 g | $67.00 $286.00 $1326.00 | 11 | |
This antagonist of GABA(A) receptors may influence the synaptic localization of MAGI-2, potentially altering its activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
As a modulator of NF-kB signaling, curcumin could indirectly influence MAGI-2, which has been implicated in this pathway. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
This inhibitor of protein biosynthesis could affect the concentration of MAGI-2 in the cell. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
This potent inhibitor of protein kinases can influence multiple signaling pathways, potentially affecting MAGI-2. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
This potent activator of Protein Kinase C (PKC) can affect multiple signaling pathways, which may influence the function or localization of MAGI-2. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
This disruptor of calcium homeostasis in the ER can influence multiple signaling pathways, potentially affecting MAGI-2. | ||||||