Date published: 2026-5-3

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Macrocycles

Santa Cruz Biotechnology now offers a broad range of macrocycles for use in various applications. Macrocycles, which are large ring molecules consisting of twelve or more atoms, are critical in scientific research due to their unique structural properties and diverse functionalities. These compounds have found extensive use in supramolecular chemistry, where their ability to form host-guest complexes makes them valuable for studying molecular recognition and self-assembly processes. Macrocycles are instrumental in materials science, as their robust frameworks and ability to encapsulate ions or molecules enable the development of advanced materials, such as sensors, catalysts, and nanomaterials. In organic synthesis, macrocycles serve as scaffolds for the construction of complex molecular architectures, facilitating the creation of compounds with specific properties and functions. Environmental chemists utilize macrocycles to develop selective binding agents for pollutant detection and removal, contributing to advancements in environmental remediation technologies. Additionally, macrocycles are crucial in the study of biological systems, where they mimic natural macrocyclic structures like enzymes and nucleic acids, providing insights into biological mechanisms and interactions. Their versatility and capability to undergo functional modifications make macrocycles indispensable tools in research, allowing scientists to explore new chemical spaces and design innovative solutions across various scientific disciplines. View detailed information on our available macrocycles by clicking on the product name.

Items 171 to 180 of 289 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1,4,8,11-tetraazacyclotetradecane Hexa(Trifluoroacetic Acid Salt)

sc-474730
100 mg
$320.00
(0)

1,4,8,11-tetraazacyclotetradecane Hexa(Trifluoroacetic Acid Salt) is a macrocyclic compound characterized by its robust nitrogen-rich framework, which facilitates strong coordination with metal ions. This unique structure promotes distinct chelation dynamics, influencing reaction kinetics and selectivity. The trifluoroacetic acid salt form enhances solubility in polar solvents, allowing for diverse interactions and complexation behaviors, making it a subject of interest in coordination chemistry.

Tildipirosin-d10

328898-40-4 unlabeledsc-474840
1 mg
$396.00
(0)

Tildipirosin-d10 is a macrocyclic compound distinguished by its intricate cyclic structure, which fosters unique conformational flexibility and spatial arrangement. This flexibility allows for selective host-guest interactions, enhancing its ability to form stable complexes with various substrates. The presence of deuterium isotopes contributes to altered vibrational properties, facilitating advanced spectroscopic studies. Its distinctive molecular architecture also influences reaction pathways, promoting specific catalytic behaviors in diverse chemical environments.

2-Desbenzoyl-2-Tiglyldocetaxel

sc-213796
1 mg
$800.00
(0)

2-Desbenzoyl-2-Tiglyldocetaxel is a macrocyclic compound characterized by its unique ring structure, which imparts significant steric hindrance and electronic effects. This configuration enables selective interactions with metal ions, enhancing its coordination chemistry. The compound exhibits notable solubility in various organic solvents, influencing its reactivity and stability. Additionally, its conformational dynamics can lead to distinct reaction kinetics, making it an intriguing subject for mechanistic studies in organic synthesis.

Rapamycin-d3 (contains d0)

392711-19-2sc-219952
1 mg
$393.00
1
(0)

Rapamycin-d3 is a macrocyclic compound distinguished by its intricate cyclic structure, which facilitates unique intramolecular interactions and hydrogen bonding patterns. This configuration enhances its ability to engage in specific molecular recognition processes, influencing its reactivity profile. The compound's isotopic labeling with deuterium provides insights into reaction mechanisms and kinetics, allowing for detailed studies of its behavior in various chemical environments. Its solubility characteristics further contribute to its versatility in diverse experimental conditions.

8-Acetoxypyrene-1,3,6-trisulfonic acid trisodium salt

115787-83-2sc-396569
sc-396569A
200 mg
1 g
$188.00
$607.00
(0)

8-Acetoxypyrene-1,3,6-trisulfonic acid trisodium salt is a macrocyclic compound characterized by its extensive sulfonic acid groups, which enhance solubility and ionic interactions in aqueous environments. The presence of acetoxy groups contributes to its unique reactivity, facilitating specific electrostatic interactions and enhancing its ability to form stable complexes with various ions. This compound exhibits distinct photophysical properties, making it suitable for studies involving fluorescence and energy transfer mechanisms.

Everolimus-d4

1338452-54-2sc-218453
1 mg
$439.00
2
(1)

Everolimus-d4 is a macrocyclic compound distinguished by its unique structural conformation, which promotes selective binding interactions with target biomolecules. Its cyclic structure allows for enhanced conformational flexibility, facilitating specific molecular recognition processes. The presence of deuterated isotopes influences reaction kinetics, providing insights into dynamic behavior in complex systems. Additionally, its hydrophobic regions contribute to unique aggregation properties, impacting solvation dynamics.

Microcystin LR, desmethyl ("Asp3-MCLR")

120011-66-7sc-477270
25 µg
$849.00
(0)

Microcystin LR, desmethyl ("Asp3-MCLR") is a macrocyclic peptide characterized by its intricate cyclic structure, which enables specific interactions with protein phosphatases. This compound exhibits a unique ability to form stable complexes, influencing enzymatic pathways and cellular signaling. Its hydrophilic and hydrophobic domains create a balance that affects solubility and membrane permeability, while its conformational rigidity enhances binding affinity, making it a subject of interest in biochemical studies.

Teicoplanin A2-4

91032-37-0sc-391672
1 mg
$235.00
(0)

Teicoplanin A2-4 is a macrocyclic glycopeptide distinguished by its complex ring structure, which facilitates selective binding to bacterial cell wall precursors. This compound exhibits unique stereochemical properties that enhance its interaction with target molecules, influencing the kinetics of transglycosylation reactions. Its amphiphilic nature contributes to its solubility profile, while the presence of multiple functional groups allows for diverse intermolecular interactions, impacting its overall stability and reactivity in various environments.

Pharacine

63440-93-7sc-477659
sc-477659A
5 mg
50 mg
$314.00
$2081.00
(0)

Pharacine is a macrocyclic compound characterized by its intricate cyclic architecture, which promotes unique conformational flexibility. This flexibility enables specific non-covalent interactions, such as hydrogen bonding and π-π stacking, enhancing its affinity for various substrates. The compound's distinct electronic properties facilitate rapid electron transfer processes, while its hydrophobic regions influence solvation dynamics, affecting its reactivity and stability in diverse chemical environments.

17-GMB-APA-GA

sc-220644
1 mg
$213.00
(0)

17-GMB-APA-GA is a macrocyclic compound distinguished by its robust ring structure, which fosters unique steric interactions and spatial orientation. This configuration allows for selective coordination with metal ions, enhancing its catalytic potential. The compound exhibits notable conformational rigidity, which influences its reaction kinetics, leading to distinct pathways in chemical transformations. Additionally, its polar and non-polar regions contribute to varied solubility profiles, impacting its behavior in different solvents.