Rapamycin-d3 (contains d0) (CAS 392711-19-2)

Rapamycin-d3 (contains d0) 85% is a deuterated analog of rapamycin, which is used in research to study the kinetics, metabolism, and molecular mechanisms of rapamycin action. The deuterium atoms (d3) replace specific hydrogen atoms in the rapamycin molecule to create a stable isotope-labeled compound. This variant is particularly useful in mass spectrometry because it provides a distinguishable mass difference from the non-deuterated form (d0), allowing for more precise quantitative analyses. In experiments where rapamycin′s effects on the mechanistic target of rapamycin (mTOR) pathway are investigated, Rapamycin-d3 can be used to trace the distribution and breakdown of the compound within biological systems. The 85% specification indicates the relative abundance of the deuterated species compared to the non-deuterated form, which is essential information for researchers when interpreting their experimental data. The use of Rapamycin-d3 in studies aids in understanding the complex biological processes modulated by rapamycin and in developing methods for the detection and quantification of this compound in various matrices.