Date published: 2026-5-3

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Macrocycles

Santa Cruz Biotechnology now offers a broad range of macrocycles for use in various applications. Macrocycles, which are large ring molecules consisting of twelve or more atoms, are critical in scientific research due to their unique structural properties and diverse functionalities. These compounds have found extensive use in supramolecular chemistry, where their ability to form host-guest complexes makes them valuable for studying molecular recognition and self-assembly processes. Macrocycles are instrumental in materials science, as their robust frameworks and ability to encapsulate ions or molecules enable the development of advanced materials, such as sensors, catalysts, and nanomaterials. In organic synthesis, macrocycles serve as scaffolds for the construction of complex molecular architectures, facilitating the creation of compounds with specific properties and functions. Environmental chemists utilize macrocycles to develop selective binding agents for pollutant detection and removal, contributing to advancements in environmental remediation technologies. Additionally, macrocycles are crucial in the study of biological systems, where they mimic natural macrocyclic structures like enzymes and nucleic acids, providing insights into biological mechanisms and interactions. Their versatility and capability to undergo functional modifications make macrocycles indispensable tools in research, allowing scientists to explore new chemical spaces and design innovative solutions across various scientific disciplines. View detailed information on our available macrocycles by clicking on the product name.

Items 161 to 170 of 289 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Phalloidin-tetramethylrhodamine conjugate

sc-362065
300 tests
$208.00
8
(1)

Phalloidin-tetramethylrhodamine conjugate, a macrocyclic compound, features a distinctive rhodamine moiety that enhances its fluorescence properties, allowing for precise visualization in biological systems. Its cyclic structure promotes strong binding to actin filaments, facilitating unique interactions that stabilize cytoskeletal dynamics. The conjugate's rigidity and planarity contribute to its effective stacking interactions, influencing its behavior in various biochemical assays and enhancing its specificity in molecular recognition processes.

Dalfopristin (as mesylate)

112362-50-2sc-362728
1 mg
$297.00
1
(0)

Dalfopristin (as mesylate), a macrocyclic compound, exhibits unique conformational flexibility that allows it to engage in specific molecular interactions. Its cyclic structure facilitates the formation of stable complexes with target biomolecules, enhancing its selectivity. The compound's ability to adopt multiple conformations influences its reaction kinetics, promoting distinct pathways in complex biochemical environments. Additionally, its hydrophobic regions contribute to unique solubility characteristics, affecting its behavior in various chemical contexts.

Erythromycin C

1675-02-1sc-362736
1 mg
$84.00
1
(0)

Erythromycin C, a macrocyclic lactone, showcases remarkable structural rigidity that influences its interaction dynamics with various substrates. Its extensive ring system allows for specific non-covalent interactions, such as hydrogen bonding and π-π stacking, which enhance its affinity for certain molecular targets. The compound's unique stereochemistry contributes to its distinct reactivity patterns, facilitating selective pathways in complex chemical reactions. Furthermore, its amphiphilic nature affects solubility and partitioning behavior in diverse environments.

Leucomycin A4

18361-46-1sc-362762
sc-362762A
1 mg
5 mg
$341.00
$1193.00
(0)

Leucomycin A4, a macrocyclic compound, exhibits a unique conformational flexibility that enables it to adapt its structure for optimal interactions with diverse molecular partners. Its intricate ring architecture facilitates specific electrostatic interactions and hydrophobic effects, influencing reaction kinetics and selectivity in various chemical processes. The compound's distinct stereochemical arrangement also plays a crucial role in modulating its reactivity, allowing for tailored pathways in synthetic applications.

Leucomycin A5

18361-45-0sc-362763
1 mg
$156.00
(0)

Leucomycin A5, a macrocyclic entity, showcases remarkable structural rigidity combined with localized flexibility, allowing it to engage in selective host-guest interactions. Its unique cyclic framework promotes specific hydrogen bonding and π-π stacking, enhancing its stability in various environments. The compound's stereochemical features contribute to its ability to form stable complexes, influencing reaction dynamics and enabling unique pathways in synthetic chemistry.

FC 131

606968-52-9sc-362738
1 mg
$430.00
(0)

FC 131, a macrocyclic compound, exhibits intriguing conformational adaptability, facilitating unique molecular interactions. Its cyclic structure allows for effective metal coordination, enhancing catalytic activity in various reactions. The compound's electron-rich regions promote strong π-π interactions, while its spatial arrangement enables selective binding with substrates. This interplay of structural features influences reaction kinetics, leading to distinct pathways in chemical transformations.

Seneciphylline N-Oxide

38710-26-8sc-473087
sc-473087A
1 mg
10 mg
$450.00
$2800.00
(0)

Seneciphylline N-Oxide, a macrocyclic compound, showcases remarkable structural rigidity combined with flexibility, allowing it to engage in diverse non-covalent interactions. Its unique ring architecture fosters intramolecular hydrogen bonding, which stabilizes specific conformations. This stabilization can influence solubility and reactivity, while the compound's ability to form host-guest complexes enhances its selectivity in molecular recognition processes. Such characteristics contribute to its distinct behavior in various chemical environments.

Talaporfin-13C4-15N

sc-473108
1 mg
$480.00
(0)

Talaporfin-13C4-15N, a macrocyclic compound, exhibits intriguing electronic properties due to its conjugated system, which facilitates efficient charge transfer. The compound's cyclic structure allows for unique π-π stacking interactions, enhancing its stability in solution. Additionally, its ability to undergo conformational changes in response to environmental stimuli can influence reaction kinetics, making it a versatile participant in complex chemical pathways. These features contribute to its distinctive behavior in various chemical contexts.

1,4,7,10-Tetratosyl-1,4,7,10-tetraazacyclododecane-d8

sc-474051
1 mg
$380.00
(0)

1,4,7,10-Tetratosyl-1,4,7,10-tetraazacyclododecane-d8 is a macrocyclic compound characterized by its robust framework that promotes selective host-guest interactions. The presence of tosyl groups enhances solubility and facilitates hydrogen bonding, leading to unique molecular recognition capabilities. Its rigid structure allows for minimal conformational flexibility, which can influence reaction kinetics and enhance stability in diverse chemical environments, making it a noteworthy subject of study in supramolecular chemistry.

Rifapentine

61379-65-5sc-212785
10 mg
$183.00
1
(1)

Rifapentine is a macrocyclic compound distinguished by its intricate ring structure that fosters unique molecular interactions. Its design allows for effective stacking and π-π interactions, enhancing its stability and reactivity. The compound exhibits selective binding properties, which can influence reaction pathways and kinetics. Additionally, its hydrophobic regions contribute to solubility variations in different solvents, making it an intriguing candidate for exploring complex chemical behaviors.