Ly-6K Activators
Ly-6K is a part of the Ly-6 superfamily of glycosylphosphatidylinositol (GPI)-anchored cell surface proteins, which are involved in various cellular processes including cell signaling and immune response regulation. However, since Ly-6K is not a conventional enzyme or receptor whose activity can be readily modulated by small molecule activators, the concept of activators in the traditional sense may not be applicable.
As a chemical class Ly-6K activators, they comprise molecules capable of binding to or interacting with Ly-6K to modulate its function. Direct activators can bind to Ly-6K and induce a conformational change that could potentially alter its interaction with other cellular components or its role in signal transduction pathways. These interactions could lead to changes in the downstream signaling events or modulate the physiological processes in which Ly-6K is involved. On the other hand, indirect activators would not bind to Ly-6K directly but would influence the protein's function through other means. This might include upregulation of Ly-6K expression, stabilization of the Ly-6K protein on the cell surface, or modulation of the cellular microenvironment that affects Ly-6K's activity. For example, modifying the lipid rafts of the cell membrane where GPI-anchored proteins like Ly-6K reside could indirectly impact Ly-6K function.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent activator of Protein Kinase C (PKC). PKC activation can lead to downstream signaling events. If Ly-6K is a part of the PKC pathway or is regulated by the PKC pathway, upregulation of PKC activity by PMA can enhance the expression or function of Ly-6K. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases the intracellular levels of cAMP, leading to the activation of protein kinase A (PKA). If Ly-6K is a part of the PKA pathway or regulated by it, Forskolin can enhance the expression or function of Ly-6K. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates the insulin receptor pathway. If Ly-6K is a part of the insulin receptor pathway or regulated by it, Insulin can enhance the expression or function of Ly-6K. | ||||||
D(+)Glucose, Anhydrous | 50-99-7 | sc-211203 sc-211203B sc-211203A | 250 g 5 kg 1 kg | $38.00 $198.00 $65.00 | 5 | |
Glucose can activate several signal transduction pathways related to metabolism. If Ly-6K is involved in these pathways or regulated by them, glucose can enhance the expression or function of Ly-6K. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid is a ligand for the retinoic acid receptor (RAR). By modulating gene expression via the RAR, it can enhance the transcription of Ly-6K if it is a target of RAR. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $98.00 $341.00 | 50 | |
LPA acts as a signaling molecule and activates the LPA receptor pathway. If Ly-6K is a part of the LPA receptor pathway or regulated by it, LPA can enhance the expression or function of Ly-6K. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a non-selective beta-adrenergic agonist. If Ly-6K is a part of the adrenergic receptor pathway or regulated by it, Isoproterenol can enhance the expression or function of Ly-6K. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate is a histone deacetylase (HDAC) inhibitor. By promoting the acetylation of histones, Sodium Butyrate can enhance the accessibility of transcription factors to the promoter region of Ly-6K and increase its transcription. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor. By preventing DNA methylation, 5-Azacytidine can enhance the expression of Ly-6K if its promoter region is normally methylated. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, a central regulator of cell growth and proliferation. If Ly-6K is a target of mTOR, Rapamycin can enhance the expression of Ly-6K in response to mTOR inhibition. | ||||||