Ly-49C Inhibitors
Ly-49C inhibitors belong to a class of chemical compounds designed to modulate the activity of Ly-49C receptors. Ly-49C receptors are a subset of natural killer (NK) cell receptors found on the surface of NK cells, which are a critical component of the innate immune system. These receptors play a crucial role in regulating NK cell activity and function. Ly-49C receptors are part of the Ly-49 receptor family, which includes several members involved in recognizing major histocompatibility complex (MHC) class I molecules and other ligands on target cells. By inhibiting Ly-49C receptors, researchers can gain insights into the regulation of NK cell responses and the mechanisms underlying immune surveillance and cytotoxicity.
Understanding the function of Ly-49C receptors is essential for unraveling the complexities of immune recognition and response. Ly-49C inhibitors are valuable tools for researchers studying NK cell biology and immunology, as they allow for the selective manipulation of Ly-49C-mediated signaling pathways. These inhibitors can be employed to investigate how Ly-49C receptors contribute to the discrimination between healthy and infected or abnormal cells, as well as their role in immune homeostasis. By exploring Ly-49C receptor inhibition, scientists aim to broaden their understanding of NK cell function and its relevance in various immune-related processes, ultimately advancing our knowledge of the innate immune system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Immunosuppressant that can inhibit NK cell activation. Might indirectly affect Ly-49C expression or function. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $78.00 $151.00 | 9 | |
Another immunosuppressant that inhibits calcineurin, potentially dampening NK cell activity and possibly Ly-49C function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Immunosuppressant that can inhibit mTOR, potentially affecting NK cell functions including Ly-49C expression. | ||||||
Imatinib mesylate | 220127-57-1 | sc-202180 sc-202180A | 25 mg 100 mg | $45.00 $111.00 | 61 | |
Tyrosine kinase inhibitor that might modulate various immune cell activities, including NK cells. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $69.00 $266.00 | 8 | |
Immunosuppressant that might affect various immune cells, potentially influencing NK cell activity. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Known to modulate immune cell trafficking; could potentially impact NK cell distribution and function. | ||||||
Lenalidomide | 191732-72-6 | sc-218656 sc-218656A sc-218656B | 10 mg 100 mg 1 g | $50.00 $374.00 $2071.00 | 18 | |
Immunomodulatory drug that can influence NK cell activity, possibly affecting Ly-49C function. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $111.00 $357.00 | 8 | |
Another immunomodulatory drug with potential effects on NK cell function. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $251.00 $500.00 $547.00 | 16 | |
JAK1/2 inhibitor that can modulate cytokine signaling, potentially influencing NK cell activity. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Tyrosine kinase inhibitor with potential to modulate immune cell functions including NK cells. | ||||||