Date published: 2026-5-17

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LTBP Antibodies

Santa Cruz Biotechnology delivers a wide array of LTBP monoclonal antibodies for investigating latent transforming growth factor-beta binding proteins. LTBP monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).LTBP proteins play a crucial role in the regulation and activation of TGF-beta, a key cytokine involved in numerous cellular processes such as cell growth, differentiation, and immune response. By binding to TGF-beta, LTBP proteins help maintain its latent form, influencing its availability and activity in the extracellular matrix. Understanding LTBP protein function is essential for elucidating their contributions to various pathological conditions, including fibrosis and cancer. Research has shown that LTBP proteins are integral to tissue development and homeostasis. LTBP expression patterns vary across different tissues and developmental stages, highlighting their specialized functions. Recent studies have revealed new insights into how LTBP proteins coordinate with other molecular partners to regulate TGF-beta bioavailability. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance our understanding of LTBP proteins and their role in human health and disease.

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LTBP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

LTBP-1 Antibody (H-1)

sc-271140mouse IgG1 κ601-740 (h)WB, IP, IF, IHC(P), ELISAh
3
(3)

LTBP-2 Antibody (E-10)

sc-166199mouse IgG2b κ211-480 (h)WB, IP, IF, ELISAm, r, h
7
(2)

LTBP-3 Antibody (H-11)

sc-390913mouse IgG1 κ1041-1250 (deletion 1082-1129) (h)WB, IP, IF, ELISAm, r, h
1
(2)

LTBP-4 Antibody (A-2)

sc-393666mouse IgM κ1558-1581 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(1)

LTBP CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LTBP-1 CRISPR/Cas9 KO Plasmid (h)

sc-402289hGene KnockoutGFP0
(0)

LTBP-1 Double Nickase Plasmid (h)

sc-402289-NIChGene KnockoutPuromycin0
(0)

LTBP-1 Double Nickase Plasmid (h2)

sc-402289-NIC-2hGene KnockoutPuromycin0
(0)

LTBP-2 Double Nickase Plasmid (h)

sc-403182-NIChGene KnockoutPuromycin0
(0)

LTBP-2 Double Nickase Plasmid (h2)

sc-403182-NIC-2hGene KnockoutPuromycin0
(0)

LTBP-3 Double Nickase Plasmid (h)

sc-404036-NIChGene KnockoutPuromycin0
(0)

LTBP-3 Double Nickase Plasmid (h2)

sc-404036-NIC-2hGene KnockoutPuromycin0
(0)

LTBP-4 CRISPR/Cas9 KO Plasmid (h)

sc-405419hGene KnockoutGFP0
(0)

LTBP CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LTBP-2 CRISPR Activation Plasmid (h)

sc-403182-ACThGene ActivationPuro, Blast, Hygro0
(0)

LTBP-3 CRISPR Activation Plasmid (h)

sc-404036-ACThGene ActivationPuro, Blast, Hygro0
(0)

LTBP-3 CRISPR Activation Plasmid (m)

sc-421482-ACTmGene ActivationPuro, Blast, Hygro0
(0)

LTBP-3 CRISPR Activation Plasmid (m2)

sc-421482-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

LTBP-3 Lentiviral Activation Particles (m)

sc-421482-LACmGene ActivationPuro, Blast, Hygro0
(0)

LTBP-4 CRISPR Activation Plasmid (h)

sc-405419-ACThGene ActivationPuro, Blast, Hygro0
(0)

LTBP-4 CRISPR Activation Plasmid (h2)

sc-405419-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LTBP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LTBP-1 siRNA (h)

sc-45454hGene SilencingN/A0
(0)

LTBP-1 shRNA Plasmid (h)

sc-45454-SHhGene SilencingPuromycin0
(0)

LTBP-1 shRNA (h) Lentiviral Particles

sc-45454-VhGene SilencingPuromycin0
(0)

LTBP-1 siRNA (m)

sc-45455mGene SilencingN/A0
(0)

LTBP-1 shRNA Plasmid (m)

sc-45455-SHmGene SilencingPuromycin0
(0)

LTBP-1 shRNA (m) Lentiviral Particles

sc-45455-VmGene SilencingPuromycin0
(0)

LTBP-2 siRNA (h)

sc-43388hGene SilencingN/A0
(0)

LTBP-2 shRNA Plasmid (h)

sc-43388-SHhGene SilencingPuromycin0
(0)

LTBP-2 shRNA (h) Lentiviral Particles

sc-43388-VhGene SilencingPuromycin0
(0)

LTBP-2 siRNA (m)

sc-43389mGene SilencingN/A0
(0)

LTBP-2 shRNA Plasmid (m)

sc-43389-SHmGene SilencingPuromycin0
(0)

LTBP-2 shRNA (m) Lentiviral Particles

sc-43389-VmGene SilencingPuromycin0
(0)

LTBP-3 siRNA (h)

sc-106921hGene SilencingN/A0
(0)

LTBP-3 shRNA Plasmid (h)

sc-106921-SHhGene SilencingPuromycin0
(0)

LTBP-3 shRNA (h) Lentiviral Particles

sc-106921-VhGene SilencingPuromycin0
(0)

LTBP-3 siRNA (m)

sc-149138mGene SilencingN/A0
(0)

LTBP-3 shRNA Plasmid (m)

sc-149138-SHmGene SilencingPuromycin0
(0)

LTBP-3 shRNA (m) Lentiviral Particles

sc-149138-VmGene SilencingPuromycin0
(0)

LTBP-4 siRNA (h)

sc-45861hGene SilencingN/A
1
(0)

LTBP-4 shRNA Plasmid (h)

sc-45861-SHhGene SilencingPuromycin
1
(0)

LTBP-4 shRNA (h) Lentiviral Particles

sc-45861-VhGene SilencingPuromycin
1
(0)

LTBP-4 siRNA (m)

sc-45862mGene SilencingN/A0
(0)

LTBP-4 shRNA Plasmid (m)

sc-45862-SHmGene SilencingPuromycin0
(0)

LTBP-4 shRNA (m) Lentiviral Particles

sc-45862-VmGene SilencingPuromycin0
(0)