LRWD1 inhibitors belong to a specific class of chemical compounds that have garnered attention in the field of molecular biology and cellular processes. LRWD1, also known as Leucine-rich repeat and WD repeat-containing protein 1, is a protein that contains leucine-rich repeats (LRRs) and WD40 repeats, which are structural motifs often found in proteins involved in protein-protein interactions and signal transduction. LRWD1 is known for its potential roles in various cellular processes, although its exact functions and molecular mechanisms are still under investigation. LRWD1 inhibitors are chemical compounds designed to interact with LRWD1, potentially modulating its functions and affecting the processes in which it is involved.
The mechanism of action of LRWD1 inhibitors typically involves their binding to specific sites or domains within the LRWD1 protein. This interaction can lead to changes in LRWD1's ability to participate in protein-protein interactions, potentially influencing signal transduction pathways, cellular responses to extracellular cues, or other processes in which LRWD1 plays a role. Consequently, LRWD1 inhibitors may have implications for understanding the molecular mechanisms underlying cell signaling, intracellular communication, and the regulation of cellular functions. They provide valuable tools for investigating the roles of LRWD1 in various cellular contexts and its impact on diverse biological processes. The study of LRWD1 inhibitors contributes to advancing our understanding of cellular regulation and protein-protein interactions, shedding light on the complex molecular networks that govern cell physiology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Binds to GC-rich DNA sequences and could interfere with transcription factors binding to the LRWD1 promoter region, reducing its expression. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $63.00 $179.00 | 11 | |
An HDAC inhibitor that could alter histone acetylation patterns and potentially downregulate LRWD1 expression through epigenetic changes. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
A cyclin-dependent kinase inhibitor that could disrupt cell cycle progression and subsequently downregulate LRWD1 expression. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Inhibits eukaryotic translation initiation, which might decrease the synthesis of the LRWD1 protein. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that may modulate the AKT signaling pathway affecting transcription factors that regulate LRWD1 expression. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
A RAF kinase inhibitor, could indirectly downregulate LRWD1 expression by affecting cell growth signaling pathways. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
Inhibits topoisomerase and induces mitochondrial dysfunction, potentially leading to decreased LRWD1 expression. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Modulates the expression of multiple genes, potentially impacting those involved in the regulation of LRWD1. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $142.00 $558.00 | 4 | |
Interacts with DNA and inhibits topoisomerase II, could indirectly downregulate LRWD1 during DNA replication and repair. | ||||||
Sanguinarium | 2447-54-3 | sc-473396 | 10 mg | $220.00 | ||
A benzophenanthridine alkaloid that can inhibit NF-kB pathway, which may result in the downregulation of LRWD1. | ||||||