LRFN2 Activators
LRFN2 Activators comprise various compounds that indirectly augment the functional activity of LRFN2, mainly through modulating pathways involved in neuronal development, survival, and synaptic plasticity. Growth factors like Brain-Derived Neurotrophic Factor (BDNF), Insulin-like Growth Factor 1 (IGF-1), and Nerve Growth Factor (NGF) are critical in this modulation. BDNF enhances LRFN2 by promoting neuronal survival and synaptic plasticity, pathways crucial for LRFN2's role in neural network formation. IGF-1's influence on neuronal growth and differentiation, and NGF's essential role in neuronal survival, further augment LRFN2's activity in synapse formation and function.
Neuregulin-1 (NRG1) and Ephrin-B2 also play significant roles in modulating LRFN2 activity. NRG1, by influencing synaptic development, and Ephrin-B2, through its interaction with Eph receptors affecting neuronal connectivity, indirectly enhance LRFN2 function in synaptic organization. Compounds like 7,8-Dihydroxyflavone, a TrkB agonist, and Forskolin, which increases cAMP levels, further contribute to LRFN2's regulation by affecting synaptic plasticity and development. Sphingosine-1-phosphate (S1P) and cyclic AMP (cAMP), through their roles in neuronal survival and intracellular signaling, respectively, also enhance LRFN2 activity in synaptic functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-Buthionine sulfoximine | 83730-53-4 | sc-200824 sc-200824A sc-200824B sc-200824C | 500 mg 1 g 5 g 10 g | $286.00 $442.00 $1532.00 $2975.00 | 26 | |
NGF, essential for neuronal survival and differentiation, indirectly enhances LRFN2 activity. It affects signaling pathways crucial for synaptic function and plasticity, where LRFN2 is active. | ||||||
7,8-Dihydroxyflavone | 38183-03-8 | sc-278634 | 100 mg | $52.00 | 2 | |
7,8-Dihydroxyflavone, a TrkB agonist, indirectly enhances LRFN2 activity by activating TrkB receptors, thereby influencing synaptic plasticity and development pathways, crucial for LRFN2 function. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin, by increasing cAMP levels, indirectly enhances LRFN2 activity. It affects neural signaling pathways related to synaptic development and plasticity, where LRFN2 plays a role. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
S1P, a signaling lipid, indirectly enhances LRFN2 activity by modulating neuronal survival and differentiation, thus influencing synaptic functions where LRFN2 is active. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
cAMP, as a secondary messenger, indirectly enhances LRFN2 activity by influencing intracellular signaling pathways related to synaptic plasticity and neuron communication, where LRFN2 is implicated. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid indirectly enhances LRFN2 activity by affecting neuronal differentiation pathways. LRFN2, involved in synaptic organization, is influenced by retinoic acid in neurodevelopmental processes. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $71.00 $202.00 | 18 | |
SB-216763 inhibits GSK-3β, indirectly enhancing LRFN2 activity by influencing pathways involved in neuronal development and synaptic plasticity, where LRFN2 is active. | ||||||