Date published: 2025-11-1

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LOC728514 Inhibitors

Staurosporine, due to its broad-spectrum kinase inhibition, can affect multiple signaling pathways, potentially intersecting with those regulated by LOC728514. Trichostatin A and Bortezomib can alter gene expression and protein stability, respectively, which can indirectly impact the function or levels of LOC728514. Thapsigargin, by disrupting calcium homeostasis, can influence any calcium-dependent role of LOC728514. PD0325901 and LY294002 are pathway-specific inhibitors that target the MAPK/ERK and PI3K/Akt pathways, respectively, which are common pathways in cell signaling that LOC728514 may be associated with.

The metabolic inhibitor 2-Deoxy-D-glucose affects cellular energy pathways, potentially impacting any metabolic role of LOC728514. Cyclopamine and Y-27632 can influence developmental pathways and cytoskeletal organization, respectively, which may be relevant to LOC728514's function if it is involved in these cellular aspects. MG-132 and Tunicamycin can affect protein turnover and folding, potentially impacting LOC728514 directly if it is a substrate for these cellular processes.

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

A non-selective protein kinase inhibitor, which can modulate multiple cell signaling pathways, potentially affecting those regulated by LOC728514.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

A histone deacetylase inhibitor that can alter gene expression, which may affect LOC728514 expression or function indirectly.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$132.00
$1064.00
115
(2)

A proteasome inhibitor that can affect protein degradation pathways, potentially altering the turnover of LOC728514 or its regulatory proteins.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$94.00
$349.00
114
(2)

An inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), which can disrupt calcium homeostasis, indirectly influencing LOC728514's function if it is calcium-dependent.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

A PI3K inhibitor that can disrupt the PI3K/Akt signaling pathway, potentially affecting LOC728514's role if it is involved in cell survival or growth signaling.

2-Deoxy-D-glucose

154-17-6sc-202010
sc-202010A
1 g
5 g
$65.00
$210.00
26
(2)

A glycolysis inhibitor that can alter cellular metabolism, potentially influencing LOC728514 if it is involved in metabolic regulation.

Cyclopamine

4449-51-8sc-200929
sc-200929A
1 mg
5 mg
$92.00
$204.00
19
(1)

A Hedgehog signaling pathway inhibitor that can alter cellular growth and differentiation, potentially affecting LOC728514's role if it is part of this pathway.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

A ROCK inhibitor that can interfere with cytoskeleton organization, potentially affecting LOC728514 if it plays a role in cell shape or motility.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

An inhibitor of the ubiquitin-proteasome pathway, which can affect protein turnover and thus potentially influence LOC728514 function.

NSC 23766

733767-34-5sc-204823
sc-204823A
10 mg
50 mg
$148.00
$597.00
75
(4)

An inhibitor of Rac1, which can modulate actin cytoskeleton organization and cell migration, potentially affecting LOC728514's role if it is involved in these processes.