The term LOC646522 Inhibitors defines a specialized class of chemical compounds intricately designed to modulate the activity of LOC646522, a molecular target currently under scientific investigation. These inhibitors are crafted through principles rooted in medicinal chemistry, with a primary focus on selectively interfering with the normal functions of LOC646522 within cellular processes. The structural features of LOC646522 Inhibitors undergo a meticulous optimization process, often involving computational modeling and structure-activity relationship studies, to refine their molecular configurations for precise binding to the target.
The significance of LOC646522 Inhibitors lies in their potential to disrupt the biochemical activities associated with LOC646522, a molecular entity believed to play a role in various biological pathways. Researchers in this field delve into the three-dimensional structure of LOC646522 and its binding interactions with inhibitors, aiming to unravel the intricate molecular mechanisms underlying inhibition. The study of LOC646522 Inhibitors contributes to a broader understanding of cellular processes, offering insights into the roles played by LOC646522 in diverse biological pathways and expanding our knowledge of the regulatory networks governing cellular activities. This research not only advances our comprehension of the molecular intricacies surrounding LOC646522 but also contributes to the broader scientific understanding of molecular targets and their involvement in fundamental cellular functions.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
These compounds inhibit RNA Polymerase II, which is responsible for the transcription of lncRNA genes like lincRNA 2743, potentially reducing its synthesis. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA and inhibits RNA polymerase, which could decrease the transcription of lncRNAs including lincRNA 2743. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB selectively inhibits RNA polymerase II-dependent transcription, possibly reducing expression of lincRNA 2743. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
This compound is a potent inhibitor of RNA polymerase II and can suppress the transcription of lncRNAs such as lincRNA 2743. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide has been shown to inhibit RNA polymerase I, II, and III, which could decrease the expression of a broad range of RNAs, including lincRNA 2743. | ||||||
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $311.00 | ||
Flavopiridol inhibits cyclin-dependent kinases which are necessary for RNA polymerase II phosphorylation and transcriptional elongation. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 is another BET bromodomain inhibitor which can change the expression of genes and lncRNAs by affecting chromatin accessibility. | ||||||
A-674563 | 552325-73-2 | sc-364393 sc-364393A | 2 mg 5 mg | $232.00 $413.00 | ||
By targeting BRD4, a member of the BET protein family, these inhibitors can disrupt the transcription of lncRNAs like lincRNA 2743. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus inhibits the mTOR pathway, which is implicated in the control of RNA polymerase III transcription of small RNAs, potentially affecting lncRNA levels indirectly. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin is an adenosine analogue that can terminate RNA chain elongation, possibly reducing lincRNA 2743 expression. |