LOC100041373 Inhibitors
LOC100041373 inhibitos can be kinase inhibitors like Staurosporine and LY294002 can impair phosphorylation events, which are crucial for the activation of many proteins. Similarly, epigenetic modulators such as 5-Azacytidine and Trichostatin A can alter the expression patterns of genes, potentially modulating the levels and function of proteins. Cell cycle inhibitors like Palbociclib can arrest cell proliferation, which may indirectly affect proteins involved in cell cycle regulation. U0126 and PD98059, both MEK inhibitors, can lead to the inhibition of the MAPK/ERK pathway, which plays a pivotal role in cell growth and differentiation.
Compounds such as Rapamycin and Bortezomib disrupt mTOR signaling and protein degradation, respectively, potentially affecting proteins regulated by these processes. Cyclopamine and Thalidomide, while targeting the Hedgehog pathway and protein degradation systems, can modulate the activity of proteins within these pathways. 2-DG, by inhibiting glycolysis, can create a state of metabolic stress, impacting proteins involved in metabolism.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a non-selective kinase inhibitor known to inhibit a wide range of protein kinases, potentially reducing phosphorylation-dependent activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is an inhibitor of phosphatidylinositol 3-kinase (PI3K), which could lead to the downregulation of PI3K/Akt signaling pathways. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine inhibits DNA methyltransferases, potentially leading to the hypomethylation and increased expression of genes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor which can lead to hyperacetylation of histones, affecting gene expression. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $315.00 | ||
Palbociclib inhibits cyclin-dependent kinases CDK4 and CDK6, which can arrest the cell cycle in the G1 phase. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor, potentially affecting cell growth, proliferation, and survival pathways. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib is a proteasome inhibitor, which could lead to the disruption of protein degradation pathways. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
Cyclopamine inhibits the Hedgehog signaling pathway, which could affect cell differentiation and proliferation. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Thalidomide modulates the degradation of certain proteins, potentially affecting the ubiquitin-proteasome system. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an MEK inhibitor, which can prevent the activation of the MAPK/ERK pathway. | ||||||