LOC100041356 Inhibitors
LOC100041356 inhibitors function through several mechanisms, for example, LY294002 and MK-2206 target the PI3K/Akt pathway, a critical axis in cellular signaling, which can control various aspects of LOC100041356 function, including its activation state and its role in cell survival. PD98059 and U0126 act on the MAPK/ERK pathway, suggesting that LOC100041356 is implicated in cellular proliferation and differentiation processes. SB203580 and SP600125 inhibit p38 MAPK and JNK, respectively, pointing to LOC100041356's involvement in cellular stress response and apoptosis.
Gefitinib and Dasatinib operate through inhibition of tyrosine kinases such as EGFR and Bcr-Abl/Src, which implies that LOC100041356 could play a role in growth factor signaling and oncogenic transformation. Rapamycin's inhibition of mTOR suggests LOC100041356 may be involved in nutrient sensing and autophagy. Y-27632 and Ibrutinib, which target ROCK and BTK respectively, suggest that LOC100041356 is associated with pathways regulating cell motility, adhesion, and immune cell function.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, thus can suppress the activation of the PI3K/Akt pathway, affecting LOC100041356. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR and can disrupt downstream signaling that may regulate LOC100041356 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK1, which can prevent activation of the MAPK/ERK pathway that can modulate LOC100041356. | ||||||
SB 202190 | 152121-30-7 | sc-202334 sc-202334A sc-202334B | 1 mg 5 mg 25 mg | $30.00 $125.00 $445.00 | 45 | |
Inhibits p38 MAPK, potentially affecting stress response pathways involving LOC100041356. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Inhibits Src family kinases, which can alter signaling cascades that may control LOC100041356 function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, which can affect the JNK signaling pathway's regulation of LOC100041356. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
Inhibits EGFR tyrosine kinase, which can impact signaling pathways influencing LOC100041356. | ||||||
MK-2206 dihydrochloride | 1032350-13-2 | sc-364537 sc-364537A | 5 mg 10 mg | $178.00 $325.00 | 67 | |
Inhibits Akt, and can thus affect downstream signaling pathways that involve LOC100041356. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Inhibits Bcr-Abl and Src kinases, potentially affecting pathways that regulate LOC100041356. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Inhibits ROCK, which can alter cell motility and morphology pathways involving LOC100041356. | ||||||