LOC100041341 Inhibitors
LOC100041341 inhibitors contain compounds like LY294002 and Rapamycin disrupt the PI3K/Akt/mTOR signaling pathway, which is central to controlling cell growth and proliferation. By impeding this pathway, these inhibitors alter the activity of LOC100041341 if it is associated with or affected by this cascade. Similarly, SB203580, PD98059, and SP600125 are selective inhibitors for components of the MAPK pathways, which are pivotal in managing cellular stress responses, apoptosis, and cell division. These inhibitors adjust the phosphorylation and activity of proteins like LOC100041341, presuming it operates within these signaling frameworks.
Bortezomib, by inhibiting the 26S proteasome, affects the degradation of proteins, potentially altering the stability and quantity of LOC100041341 in the cell. Kinase inhibitors such as Sorafenib, PP2, and Dasatinib target tyrosine kinases and could thereby regulate the phosphorylation and functionality of LOC100041341 if it is a substrate or influenced by these enzymes. Thapsigargin and U73122 disturb calcium homeostasis and phospholipase C signaling, respectively, which could lead to modifications in proteins regulated by calcium or by inositol triphosphate and diacylglycerol, molecules produced by phospholipase C activity. Go6983 inhibits protein kinase C, which can also affect the phosphorylation state and activity of LOC100041341 if it is regulated by PKC-mediated pathways.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, leading to reduced Akt phosphorylation and subsequent downregulation of downstream targets within the PI3K/Akt/mTOR pathway, affecting LOC100041341 activity if it is regulated by this pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Binds to FKBP12 and inhibits mTOR, altering the function of proteins associated with the mTOR pathway, including LOC100041341 if it is a downstream effector. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Selectively inhibits p38 MAPK, potentially altering the phosphorylation state and function of proteins influenced by p38 MAPK signaling, including LOC100041341. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK1/2, preventing the activation of ERK pathway and potentially modulating the activity of proteins like LOC100041341 associated with this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, affecting proteins regulated by stress responses and apoptotic signaling pathways, including LOC100041341 if it is JNK-related. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Inhibits the 26S proteasome, leading to accumulation of ubiquitinated proteins and potential alteration of protein levels including LOC100041341 if it is prone to proteasomal degradation. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Inhibits multiple tyrosine kinases, potentially impacting signaling pathways that regulate proteins like LOC100041341. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Inhibits Src family kinases, altering signaling pathways that rely on tyrosine phosphorylation, which may modulate the activity of LOC100041341. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Inhibits Bcr-Abl and Src family kinases, which could affect the phosphorylation and activation state of proteins such as LOC100041341 associated with these kinases. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Inhibits the SERCA pump disrupting calcium homeostasis, potentially impacting the function of calcium-regulated proteins including LOC100041341. | ||||||