LOC100041324 Inhibitors
LY294002, SB203580, and SP600125 target the PI3K/AKT, p38 MAPK, and JNK signaling pathways, respectively. These pathways are essential for a variety of cellular functions, including cell survival, growth, inflammation, stress response, and apoptosis. By altering these pathways, these inhibitors can change the cellular context and indirectly influence the activity of LOC100041324. PD98059 and Rapamycin target the MEK enzyme within the MAPK/ERK pathway and the mTOR pathway, which are central to cell proliferation and growth signaling.
Gefitinib and Y-27632 focus on the EGFR and Rho/ROCK pathways, which dictate cell proliferation, survival, and cytoskeletal dynamics. Blebbistatin and Bortezomib alter myosin II activity and proteasomal protein degradation, potentially impacting cellular motility and protein stability, respectively. ZM-447439 interferes with cell division by inhibiting Aurora kinases, which could affect LOC100041324 if it plays a role in mitotic processes Thapsigargin and 2-Deoxy-D-glucose disrupt intracellular calcium homeostasis and energy metabolism, suggesting that if LOC100041324 is involved in calcium signaling or energy-dependent processes, these inhibitors could modulate its function.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor that can prevent the activation of downstream signaling, potentially affecting LOC100041324 if it is part of the PI3K/AKT pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor that can disrupt inflammatory responses and cell differentiation processes, potentially affecting LOC100041324 if it is part of the p38 MAPK pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that can modulate stress responses and apoptosis, potentially influencing LOC100041324 if it is involved in the JNK signaling pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor that can block the MAPK/ERK pathway, potentially affecting LOC100041324 if it operates within this pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor that can inhibit cell growth and proliferation, potentially affecting LOC100041324 if it is part of the mTOR signaling pathway. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
EGFR inhibitor that can disrupt cell proliferation and survival, potentially affecting LOC100041324 if it is associated with the EGFR signaling pathway. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
ROCK inhibitor that can alter cell shape and motility, potentially affecting LOC100041324 if it is involved in the Rho/ROCK pathway. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
Myosin II inhibitor that can impair cell contraction and migration, potentially influencing LOC100041324 if it is involved in cellular motility. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Proteasome inhibitor that can disrupt protein degradation, potentially affecting LOC100041324 stability if it is regulated by ubiquitination. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
Aurora kinase inhibitor that can disrupt cell division, potentially affecting LOC100041324 if it is involved in mitosis. | ||||||