LOC100041202 can be inhibited by compounds such as LY294002 and Rapamycin are pivotal in their capacity to disrupt the PI3K/AKT/mTOR pathway, a major conduit of cell growth and survival signals that LOC100041202 may be a part of. Inhibitors like SP600125 and U0126 are essential for their roles in modulating the MAPK/ERK and JNK signaling cascades, which are integral to cell proliferation, differentiation, apoptosis, and stress responses. PP2 and Ibrutinib provide important insights into the regulation of tyrosine kinase-mediated signaling, a pathway where LOC100041202 could be active. Further down the signaling cascade, compounds like Dorsomorphin and Bortezomib offer a means to impact cellular metabolism and proteostasis, which are crucial for maintaining cellular equilibrium and could be areas where LOC100041202 has a role.
Dasatinib and Imatinib provide a targeted approach to disrupt oncogenic signaling in cancer cells, which could be a process where LOC100041202 is implicated. Palbociclib's inhibition of cell cycle kinases and Venetoclax's targeting of anti-apoptotic proteins exemplify the strategic disruption of cell cycle control and apoptotic regulation that could be vital to the regulatory functions of LOC100041202. Collectively, these inhibitors form a comprehensive approach to indirectly modulate the activity of LOC100041202. They are not only indicative of the possible regulatory scope of LOC100041202 within various cellular contexts but also represent a sophisticated toolkit for influencing the protein's involvement in critical cellular functions. This approach to inhibition through the modulation of related pathways provides a broad perspective on the potential mechanisms by which the activity of LOC100041202 can be altered.
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Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibits PI3K, can alter AKT signaling and related survival pathways LOC100041202 may be part of. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, can suppress protein synthesis and cell growth LOC100041202 may influence. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, can affect apoptosis and inflammatory responses LOC100041202 might regulate. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
Inhibits Src family kinases, can affect cell adhesion, growth, and differentiation involving LOC100041202. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $156.00 | 5 | |
Inhibits Bruton's tyrosine kinase, can disrupt B-cell receptor signaling LOC100041202 could engage in. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $96.00 $355.00 | 69 | |
Inhibits AMPK, can alter energy homeostasis and metabolism pathways LOC100041202 is part of. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Inhibits proteasome, can induce cell cycle arrest and apoptosis LOC100041202 may affect. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Inhibits BCR-ABL and Src family kinases, can interfere with proliferation and survival signals LOC100041202 may play a role in. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $26.00 $119.00 $213.00 | 27 | |
Inhibits BCR-ABL, c-Kit, and PDGFR, can alter growth factor signaling LOC100041202 might participate in. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
Inhibits CDK4/6, can halt cell cycle progression LOC100041202 may be critical for. | ||||||