The chemical class of LOC100040839 Inhibitors pertains to a specific set of compounds designed to target and inhibit the activity of the gene product expressed by LOC100040839. This gene, identified through advanced genomic sequencing and research, plays a crucial role in various cellular mechanisms and processes. The functionality of LOC100040839 is highly dependent on the cellular context, with its role varying according to different environmental and intracellular conditions. The inhibitors developed for this gene are characterized by their ability to selectively interact with the proteins or enzymes produced as a consequence of LOC100040839 expression. This targeted binding is key to their mechanism of action, as it directly impacts the biochemical pathways involving the LOC100040839 gene product. The primary aim of these inhibitors is to modulate the activity of this gene product, thereby influencing the associated cellular processes and outcomes.
The development of LOC100040839 Inhibitors is an intricate and interdisciplinary process, integrating aspects of molecular biology, biochemistry, and structural biology. The initial phase of developing these inhibitors involves gaining an in-depth understanding of the structure and function of the LOC100040839 gene product. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are instrumental in providing detailed insights into the target molecule. This foundational knowledge enables the rational design of inhibitors that are effective in their interaction with the target and exhibit high selectivity. These inhibitors are generally small molecules, formulated to efficiently penetrate cell membranes and establish a stable and potent interaction with their target. The molecular design of these inhibitors is meticulously optimized, ensuring strong interactions with the target molecule, typically involving hydrogen bonds, hydrophobic interactions, and van der Waals forces. The efficacy of these inhibitors is evaluated through a series of biochemical assays in vitro. These assays are crucial for assessing the inhibitors' potency, specificity, and overall behavior under controlled experimental conditions. This research is vital for understanding the inhibitors' mechanism of action and for further investigations into their interaction dynamics and potential influence on cellular functions and pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase and potentially decreasing gene expression genome-wide. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Alpha-amanitin is an inhibitor of RNA polymerase II, potentially reducing mRNA synthesis and gene expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide inhibits the activity of RNA polymerase I, II, and III, potentially decreasing overall gene expression. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine intercalates into DNA and inhibits DNA and RNA polymerase activity, possibly decreasing gene expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB is an adenosine analog that inhibits RNA polymerase II, potentially reducing gene expression. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin is an adenosine analog that can terminate mRNA elongation, potentially reducing gene expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin inhibits topoisomerase I, leading to DNA damage and potentially affecting gene expression. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide inhibits topoisomerase II, which can cause DNA damage and potentially alter gene expression. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol is a cyclin-dependent kinase inhibitor, potentially affecting cell cycle progression and gene expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to DNA and inhibits RNA polymerase, potentially reducing gene expression. | ||||||