The chemical class known as LOC100040491 Inhibitors comprises a range of compounds meticulously designed to specifically inhibit the activity of the gene product of LOC100040491. This gene, identified through extensive genomic research, plays an integral role in a variety of cellular processes. Its function, however, is highly context-dependent, varying with the cellular environment and external stimuli. The inhibitors targeting LOC100040491 are engineered to selectively interact with the proteins or enzymes that result from the gene's expression. This interaction is crucial for the mechanism of these inhibitors, as they aim to directly modulate the biochemical pathways involving the LOC100040491 gene product. By inhibiting the activity of this gene product, these compounds can significantly impact the associated cellular functions.
Developing LOC100040491 Inhibitors is an intricate process that blends molecular biology, chemistry, and bioinformatics. At the core of this development is a deep understanding of the structure and function of the LOC100040491 gene product. Techniques like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are extensively used to gain insights into the target molecule. This comprehensive understanding is crucial for the rational design of inhibitors that are effective and highly specific to their target. Typically, these inhibitors are small molecules, designed to efficiently penetrate cell membranes and engage in stable and potent interactions with their target. The molecular design of these inhibitors is carefully optimized to ensure robust interactions with the target molecule, usually involving the formation of hydrogen bonds, hydrophobic interactions, and van der Waals forces. The efficacy of these inhibitors is rigorously tested through a series of biochemical assays. These assays are essential in determining the potency, specificity, and overall interaction profile of the inhibitors, providing insights into their behavior in controlled experimental conditions. Such studies are vital for understanding the inhibitors' mechanism of action and for laying the groundwork for further research into their interaction dynamics and impact on cellular pathways.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferases, which could result in hypomethylation of DNA and affect gene expression patterns. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor which can alter chromatin structure and potentially impact transcription of genes. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Another histone deacetylase inhibitor that may lead to changes in chromatin architecture, affecting gene expression indirectly. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A short-chain fatty acid that serves as an inhibitor of histone deacetylases, influencing gene expression through epigenetic modifications. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
A non-nucleoside DNA methyltransferase inhibitor that could lead to DNA demethylation and altered gene expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Binds to GC-rich sequences in DNA, potentially preventing binding of transcription factors to promoters and affecting gene expression. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Known to intercalate into DNA and RNA, which can disrupt replication, transcription, and post-transcriptional events. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Has been shown to act as a tyrosine kinase inhibitor, and may modulate transcription factor activity and gene expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Another DNA methyltransferase inhibitor, leading to DNA hypomethylation and potential changes in gene expression. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
A selective histone deacetylase inhibitor that can modulate chromatin structure and gene expression. |