LDHC inhibitors constitute a distinct subset of chemical compounds that have attracted scientific scrutiny for their ability to modulate specific facets of cellular dynamics. This class of inhibitors is purposefully crafted to interact with LDHC (Lactate Dehydrogenase C), a foundational enzyme in cellular metabolism. LDHC occupies a critical role in catalyzing the conversion of pyruvate to lactate, a pivotal step in metabolic pathways. This conversion holds particular significance across a spectrum of physiological conditions, contributing significantly to energy production and metabolic stability. Engineered with meticulous precision, LDHC inhibitors are tailored to selectively bind to the LDHC enzyme, thereby disrupting its normative enzymatic activity.
This targeted disruption positions LDHC inhibitors as influencers of cellular metabolic processes, perturbing the delicate equilibrium between pyruvate and lactate levels. The modulation of LDHC through these inhibitors carries broader implications for cellular adaptation and responses to a diverse array of environmental stimuli. As researchers meticulously investigate the intricate mechanics of LDHC inhibitors and their nuanced interplay with cellular metabolism, they strive to unravel the broader implications of modifying LDHC's operational dynamics. This scientific exploration contributes to a heightened understanding of cellular biology, shedding light on ramifications that extend across various cellular contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium oxamate | 565-73-1 | sc-215880 sc-215880B sc-215880C sc-215880D sc-215880A | 5 g 100 g 250 g 1 kg 25 g | $77.00 $469.00 $1106.00 $4111.00 $152.00 | 14 | |
Competitive inhibitor of LDH that competes with pyruvate for its binding site, inhibiting the conversion of pyruvate to lactate. | ||||||
2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid | 213971-34-7 | sc-498807 | 1 mg | $480.00 | ||
LDH inhibitor that reduces lactate production by inhibiting the enzyme's activity, potentially altering cancer cell metabolism. | ||||||
Galloflavin | 568-80-9 | sc-489548 | 10 mg | $380.00 | ||
Inhibits LDH activity and lactate production, possibly impacting cancer cell metabolism and survival. | ||||||
Febuxostat | 144060-53-7 | sc-207680 | 10 mg | $168.00 | 3 | |
LDH inhibitor that could disrupt lactate production by binding to the enzyme's active site. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
May inhibit LDH activity, potentially affecting lactate production and cancer cell metabolism. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $31.00 $89.00 $135.00 $443.00 | 13 | |
Indirectly inhibits LDH by affecting upstream metabolic pathways, potentially altering lactate production. | ||||||
Lonidamine | 50264-69-2 | sc-203115 sc-203115A | 5 mg 25 mg | $105.00 $364.00 | 7 | |
Disrupts LDH activity and glycolysis, potentially reducing lactate production and altering cancer cell metabolism. | ||||||