Date published: 2025-11-20

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LASS Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of LASS Antibodies for advanced research in lipid metabolism and cellular signaling. LASS Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). LASS proteins, or Longevity Assurance Genes, play a crucial role in the synthesis of sphingolipids, which are essential for cell membrane integrity and signaling pathways. The involvement of LASS proteins in regulating apoptosis and cellular stress responses makes them significant targets in cancer research and neurodegenerative diseases. Understanding LASS protein function can provide insights into therapeutic targets for various conditions. Researchers worldwide utilize LASS monoclonal antibodies to advance their studies in sphingolipid metabolism. The relationship between LASS proteins and cellular homeostasis continues to reveal new possibilities in disease treatment. LASS monoclonal antibodies from Santa Cruz Biotechnology enable researchers to make meaningful contributions to scientific understanding of lipid biology and its implications in health and disease.

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LASS Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

LASS1 Antibody (3F9)

sc-293497mouse IgG2a κ301-350 (h)WB, IP, ELISAh
1
(2)

LASS2 Antibody (C-11)

sc-390745mouse IgG1 κ141-180 (h)WB, IP, IF, IHC(P), ELISAm, r, h
6
(7)

LASS4 Antibody (D-6)

sc-376497mouse IgG1 κ326-394 (h)WB, IP, IF, ELISAh
1
(1)

LASS6 Antibody (L-18)

sc-100554mouse IgG2a κ62-132 (h)WB, IP, IF, IHC(P), ELISAm, r, h
11
(6)

LASS CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LASS1 CRISPR/Cas9 KO Plasmid (h)

sc-405614hGene KnockoutGFP0
(0)

LASS1 HDR Plasmid (h)

sc-405614-HDRhHomology Directed RepairPuromycin0
(0)

LASS1 Double Nickase Plasmid (h)

sc-405614-NIChGene KnockoutPuromycin0
(0)

LASS1 Double Nickase Plasmid (h2)

sc-405614-NIC-2hGene KnockoutPuromycin0
(0)

LASS2 CRISPR/Cas9 KO Plasmid (h2)

sc-403112-KO-2hGene KnockoutGFP0
(0)

LASS2 Double Nickase Plasmid (h)

sc-403112-NIChGene KnockoutPuromycin0
(0)

LASS2 Double Nickase Plasmid (h2)

sc-403112-NIC-2hGene KnockoutPuromycin0
(0)

LASS3 CRISPR/Cas9 KO Plasmid (h)

sc-409070hGene KnockoutGFP0
(0)

LASS3 HDR Plasmid (h)

sc-409070-HDRhHomology Directed RepairPuromycin0
(0)

LASS3 Double Nickase Plasmid (h)

sc-409070-NIChGene KnockoutPuromycin0
(0)

LASS3 Double Nickase Plasmid (h2)

sc-409070-NIC-2hGene KnockoutPuromycin0
(0)

LASS4 CRISPR/Cas9 KO Plasmid (h)

sc-406329hGene KnockoutGFP0
(0)

LASS4 HDR Plasmid (h)

sc-406329-HDRhHomology Directed RepairPuromycin0
(0)

LASS4 Double Nickase Plasmid (h)

sc-406329-NIChGene KnockoutPuromycin0
(0)

LASS4 Double Nickase Plasmid (h2)

sc-406329-NIC-2hGene KnockoutPuromycin0
(0)

LASS5 CRISPR/Cas9 KO Plasmid (h)

sc-404525hGene KnockoutGFP0
(0)

LASS5 HDR Plasmid (h)

sc-404525-HDRhHomology Directed RepairPuromycin0
(0)

LASS5 Double Nickase Plasmid (h)

sc-404525-NIChGene KnockoutPuromycin0
(0)

LASS5 Double Nickase Plasmid (h2)

sc-404525-NIC-2hGene KnockoutPuromycin0
(0)

LASS6 CRISPR/Cas9 KO Plasmid (h)

sc-403901hGene KnockoutGFP0
(0)

LASS6 HDR Plasmid (h)

sc-403901-HDRhHomology Directed RepairPuromycin0
(0)

LASS6 Double Nickase Plasmid (h)

sc-403901-NIChGene KnockoutPuromycin0
(0)

LASS6 Double Nickase Plasmid (h2)

sc-403901-NIC-2hGene KnockoutPuromycin0
(0)

LASS CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LASS1 CRISPR Activation Plasmid (h)

sc-405614-ACThGene ActivationPuro, Blast, Hygro0
(0)

LASS1 CRISPR Activation Plasmid (h2)

sc-405614-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS1 Lentiviral Activation Particles (h)

sc-405614-LAChGene ActivationPuro, Blast, Hygro0
(0)

LASS1 Lentiviral Activation Particles (h2)

sc-405614-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS2 CRISPR Activation Plasmid (h)

sc-403112-ACThGene ActivationPuro, Blast, Hygro0
(0)

LASS2 CRISPR Activation Plasmid (h2)

sc-403112-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS2 Lentiviral Activation Particles (h)

sc-403112-LAChGene ActivationPuro, Blast, Hygro0
(0)

LASS2 Lentiviral Activation Particles (h2)

sc-403112-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS3 CRISPR Activation Plasmid (h)

sc-409070-ACThGene ActivationPuro, Blast, Hygro0
(0)

LASS3 CRISPR Activation Plasmid (h2)

sc-409070-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS3 Lentiviral Activation Particles (h)

sc-409070-LAChGene ActivationPuro, Blast, Hygro0
(0)

LASS3 Lentiviral Activation Particles (h2)

sc-409070-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS4 CRISPR Activation Plasmid (h)

sc-406329-ACThGene ActivationPuro, Blast, Hygro0
(0)

LASS4 CRISPR Activation Plasmid (h2)

sc-406329-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS4 Lentiviral Activation Particles (h)

sc-406329-LAChGene ActivationPuro, Blast, Hygro0
(0)

LASS4 Lentiviral Activation Particles (h2)

sc-406329-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS5 CRISPR Activation Plasmid (h)

sc-404525-ACThGene ActivationPuro, Blast, Hygro0
(0)

LASS5 CRISPR Activation Plasmid (h2)

sc-404525-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS5 Lentiviral Activation Particles (h)

sc-404525-LAChGene ActivationPuro, Blast, Hygro0
(0)

LASS5 Lentiviral Activation Particles (h2)

sc-404525-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS6 CRISPR Activation Plasmid (h)

sc-403901-ACThGene ActivationPuro, Blast, Hygro0
(0)

LASS6 CRISPR Activation Plasmid (h2)

sc-403901-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS6 Lentiviral Activation Particles (h)

sc-403901-LAChGene ActivationPuro, Blast, Hygro0
(0)

LASS6 Lentiviral Activation Particles (h2)

sc-403901-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

LASS siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LASS1 siRNA (h)

sc-62543hGene SilencingN/A
2
(0)

LASS1 shRNA Plasmid (h)

sc-62543-SHhGene SilencingPuromycin
2
(0)

LASS1 shRNA (h) Lentiviral Particles

sc-62543-VhGene SilencingPuromycin
2
(0)

LASS1 siRNA (m)

sc-62544mGene SilencingN/A0
(0)

LASS1 shRNA Plasmid (m)

sc-62544-SHmGene SilencingPuromycin0
(0)

LASS1 shRNA (m) Lentiviral Particles

sc-62544-VmGene SilencingPuromycin0
(0)

LASS2 siRNA (h)

sc-62545hGene SilencingN/A0
(0)

LASS2 shRNA Plasmid (h)

sc-62545-SHhGene SilencingPuromycin0
(0)

LASS2 shRNA (h) Lentiviral Particles

sc-62545-VhGene SilencingPuromycin0
(0)

LASS2 siRNA (m)

sc-62546mGene SilencingN/A
1
(0)

LASS2 shRNA Plasmid (m)

sc-62546-SHmGene SilencingPuromycin
1
(0)

LASS2 shRNA (m) Lentiviral Particles

sc-62546-VmGene SilencingPuromycin
1
(0)

LASS3 siRNA (h)

sc-62547hGene SilencingN/A0
(0)

LASS3 shRNA Plasmid (h)

sc-62547-SHhGene SilencingPuromycin0
(0)

LASS3 shRNA (h) Lentiviral Particles

sc-62547-VhGene SilencingPuromycin0
(0)

LASS3 siRNA (m)

sc-62548mGene SilencingN/A0
(0)

LASS3 shRNA Plasmid (m)

sc-62548-SHmGene SilencingPuromycin0
(0)

LASS3 shRNA (m) Lentiviral Particles

sc-62548-VmGene SilencingPuromycin0
(0)

LASS4 siRNA (h)

sc-62549hGene SilencingN/A0
(0)

LASS4 shRNA Plasmid (h)

sc-62549-SHhGene SilencingPuromycin0
(0)

LASS4 shRNA (h) Lentiviral Particles

sc-62549-VhGene SilencingPuromycin0
(0)

LASS4 siRNA (m)

sc-62550mGene SilencingN/A0
(0)

LASS4 shRNA Plasmid (m)

sc-62550-SHmGene SilencingPuromycin0
(0)

LASS4 shRNA (m) Lentiviral Particles

sc-62550-VmGene SilencingPuromycin0
(0)

LASS5 siRNA (h)

sc-62551hGene SilencingN/A0
(0)

LASS5 shRNA Plasmid (h)

sc-62551-SHhGene SilencingPuromycin0
(0)

LASS5 shRNA (h) Lentiviral Particles

sc-62551-VhGene SilencingPuromycin0
(0)

LASS5 siRNA (m)

sc-62552mGene SilencingN/A0
(0)

LASS5 shRNA Plasmid (m)

sc-62552-SHmGene SilencingPuromycin0
(0)

LASS5 shRNA (m) Lentiviral Particles

sc-62552-VmGene SilencingPuromycin0
(0)

LASS6 siRNA (h)

sc-62553hGene SilencingN/A0
(0)

LASS6 shRNA Plasmid (h)

sc-62553-SHhGene SilencingPuromycin0
(0)

LASS6 shRNA (h) Lentiviral Particles

sc-62553-VhGene SilencingPuromycin0
(0)

LASS6 siRNA (m)

sc-62554mGene SilencingN/A0
(0)

LASS6 shRNA Plasmid (m)

sc-62554-SHmGene SilencingPuromycin0
(0)

LASS6 shRNA (m) Lentiviral Particles

sc-62554-VmGene SilencingPuromycin0
(0)