Date published: 2026-6-9

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LASS Inhibitors

Santa Cruz Biotechnology now offers a broad range of LASS Inhibitors for use in various applications. LASS Inhibitors target the longevity assurance homolog (LASS) family of enzymes, also known as ceramide synthases, which are crucial for the biosynthesis of ceramides. Ceramides are key components of the cell membrane and play vital roles in cellular signaling pathways, influencing processes such as apoptosis, cell differentiation, and stress responses. By inhibiting LASS enzymes, researchers can study the impact of decreased ceramide production on cellular functions and explore the regulatory mechanisms of sphingolipid metabolism. LASS Inhibitors are important tools in scientific research for dissecting the complex interactions between ceramide synthesis and cellular physiology, providing insights into how changes in lipid composition affect cellular signaling and function. These inhibitors are also utilized in high-throughput screening assays to identify novel modulators of ceramide metabolism, aiding in the discovery of new regulatory pathways and potential research targets. The use of LASS Inhibitors supports the development of experimental models that advance our understanding of lipid biology and its implications in various biological contexts. View detailed information on our available LASS Inhibitors by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Fumonisin B1

116355-83-0sc-201395
sc-201395A
1 mg
5 mg
$200.00
$680.00
18
(1)

Fumonisin B1 acts as a significant inhibitor of ceramide synthase, disrupting sphingolipid metabolism. Its unique structure allows for specific binding to the active site of the enzyme, leading to altered lipid signaling pathways. The compound exhibits a high affinity for lipid membranes, influencing membrane fluidity and integrity. Additionally, its interactions with cellular receptors can trigger downstream effects, highlighting its role in modulating cellular responses.

Fumonisin B2

116355-84-1sc-201393
sc-201393A
1 mg
5 mg
$318.00
$1104.00
1
(1)

Fumonisin B2 is a potent disruptor of sphingolipid biosynthesis, exhibiting a unique ability to interfere with the enzymatic activity of ceramide synthase. Its structural conformation facilitates selective interactions with lipid bilayers, impacting membrane dynamics and permeability. The compound's kinetic profile reveals a rapid onset of inhibition, which can lead to significant alterations in cellular signaling cascades. Furthermore, Fumonisin B2's affinity for specific lipid domains underscores its role in modulating cellular homeostasis.