KRTAP4-7 Inhibitors
KRTAP4-7 inhibitors belong to a class of chemical compounds specifically designed to selectively target and interfere with the activity of KRTAP4-7, a protein found within the Keratin-Associated Protein (KRTAP) family. These proteins are predominantly expressed in hair and hair follicles, where they play vital roles in shaping the structural and mechanical properties of hair fibers. KRTAP4-7, as a member of this family, is presumed to contribute to the structural integrity and functional characteristics of hair.
The primary mechanism of action for KRTAP4-7 inhibitors typically involves their interaction with the KRTAP4-7 protein or its associated molecules, leading to the modulation of its normal function. By inhibiting KRTAP4-7, these compounds have the ability to influence processes related to hair development, hair structure, or other cellular functions in which this protein is involved. However, the exact functions and molecular pathways associated with KRTAP4-7 are still subjects of active investigation. Scientists studying KRTAP4-7 inhibitors aim to uncover the precise roles and significance of KRTAP4-7 within the context of hair biology and other relevant cellular processes. These inhibitors serve as valuable tools for advancing our understanding of KRTAP4-7 and its roles in cellular functions. In this context, they contribute to expanding our knowledge of the complex interactions and functions of keratin-associated proteins in the biology of hair and related tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate is a short-chain fatty acid that acts as a histone deacetylase inhibitor, potentially reducing the expression of certain genes by altering chromatin structure. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $145.00 $569.00 | 4 | |
Ellipticine intercalates into DNA and can inhibit various DNA and RNA polymerases, which may lead to a decrease in gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a polyphenol found in green tea that may modulate gene expression through epigenetic changes, affecting DNA methylation and histone acetylation. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin interferes with protein synthesis by inhibiting peptidyl transferase activity on ribosomes, potentially reducing protein levels globally. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $64.00 $183.00 | 11 | |
Scriptaid is another histone deacetylase inhibitor that can alter acetylation patterns on histones, affecting gene expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD 98059 is a MAP kinase inhibitor that can block signal transduction pathways, potentially leading to reduced transcription of certain genes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that could disrupt signal transduction pathways, possibly downregulating expression of various proteins. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 inhibits MEK1/2, which interrupts the MAPK/ERK signal transduction pathway that can affect gene transcription. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine has been shown to inhibit various DNA and RNA polymerases and may affect gene expression indirectly through these mechanisms. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane affects the expression of genes involved in detoxification and antioxidant responses and may alter the expression of other genes as well. | ||||||