KLH is a large, multi-subunit, oxygen-carrying protein found in the hemolymph of the marine gastropod, the Keyhole Limpet (genus Megathura).Hemocyanins, including KLH, are copper-containing proteins that bind and transport oxygen in many mollusks and arthropods. They're notable for their blue color when oxygenated. KLH, in particular, is of significant interest to biomedical research and development due to its strong immunogenic properties.KLH is composed of two distinct subunits known as KLH1 and KLH2, which are assembled into large, cylindrical structures. Each subunit is built from multiple copies of a ~350 kDa protein, which associate to form the decameric subunits. These can then aggregate into didecamers or multidecamers to form the functional hemocyanin.
The KLH protein is often used as a carrier protein in vaccine development because it can stimulate the immune system and enhance the body's response to an associated antigen. However, the specific structure and immunogenic properties can vary between KLH1 and KLH2.If "Keyhole Limpet Hemocyanin A" refers to a specific subunit or variant of KLH, I recommend checking the latest research or reaching out to experts in the field for more information. It's also important to note that ethical considerations should be taken into account when using KLH, as the Keyhole Limpet is a non-domesticated species collected from the wild.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $663.00 | 2 | |
A synthetic analog of double-stranded RNA, used as an immune stimulant in vaccine preparations including KLH. | ||||||
Squalene | 111-02-4 | sc-281155 sc-281155A sc-281155B | 10 ml 100 ml 500 ml | $49.00 $92.00 $215.00 | 1 | |
An organic compound used in some adjuvant formulations to enhance immune response to KLH in vaccines. | ||||||
Chitosan | 9012-76-4 | sc-221421 sc-221421A sc-221421B sc-221421D sc-221421C | 10 g 25 g 100 g 8 kg 500 g | $41.00 $55.00 $135.00 $3339.00 $298.00 | 6 | |
Used as a delivery system in vaccine formulations, potentially enhancing the immune response to KLH. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
Toll-like receptor agonists can be used to stimulate the immune system in KLH-based vaccine formulations. | ||||||
GM-CSF | 83869-56-1 | sc-280759 | 5 µg | $516.00 | 1 | |
Sometimes used as an adjuvant to enhance immune responses to KLH in vaccine settings. | ||||||