KLC3 Activators
Kinesins, including KLC3, are motor proteins that move along microtubule networks within cells, carrying various cargoes. They are essential for numerous cellular processes, such as mitosis, meiosis, and transport of organelles. The activity of kinesins is closely tied to the dynamics of microtubules. Chemicals like Paclitaxel and Taxol stabilize microtubules, enhancing the efficiency of kinesin-mediated transport, while agents like Nocodazole and Vinblastine disrupt microtubule assembly, affecting kinesin function. ATP is fundamentally required for the motor activity of kinesins, serving as an energy source for their movement.
The indirect activators listed, while not specific to KLC3, provide insight into the modulation of kinesin activities and can guide research into the specific regulation of KLC3. The influence of these chemicals ranges from direct effects on microtubule stability to broader impacts on cellular signaling pathways that may affect kinesin function. Understanding the interaction between these activators and KLC3 can shed light on the mechanistic aspects of intracellular transport and the role of KLC3 in these processes.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ATP | 56-65-5 | sc-507511 | 5 g | $17.00 | ||
Directly required for the motor activity of kinesins, including potential effects on KLC3. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules, potentially enhancing the efficiency of kinesin-mediated transport. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
A microtubule destabilizer, indirectly affects kinesin function by altering microtubule dynamics. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Known to influence microtubule dynamics, potentially impacting kinesin interactions. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Disrupts microtubule assembly, indirectly influencing kinesin-mediated transport. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Inhibits microtubule polymerization, indirectly affecting kinesin-related transport processes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Has been shown to affect microtubule dynamics, potentially influencing kinesin activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences numerous cellular pathways, including those that may interact with kinesin function. | ||||||
Monastrol | 254753-54-3 | sc-202710 sc-202710A | 1 mg 5 mg | $120.00 $233.00 | 10 | |
Specifically inhibits kinesin Eg5; its effect on KLC3 could be through altered kinesin interactions. | ||||||