IQSEC1 Inhibitors
IQSEC1 inhibitors constitute a class of chemical compounds specifically designed to target and interfere with the activity of IQSEC1, also known as IQ motif and SEC7 domain-containing protein 1. IQSEC1 is a protein that plays a role in cellular processes related to intracellular trafficking and membrane dynamics. While it is not as extensively studied as some other proteins, it is believed to be involved in regulating the exchange of lipids on cellular membranes and is associated with intracellular vesicle transport.
The primary mechanism of action for IQSEC1 inhibitors typically involves their interaction with the IQSEC1 protein or its associated molecules, disrupting its normal functions. By inhibiting IQSEC1, these compounds have the potential to impact cellular processes related to membrane dynamics and intracellular trafficking. Researchers studying IQSEC1 inhibitors aim to elucidate the specific roles and functions of IQSEC1 within cellular biology, contributing to our understanding of its significance in various biological contexts. These inhibitors serve as valuable tools for advancing our knowledge of less-characterized proteins, facilitating the exploration of new areas of molecular and cellular biology research. In this context, they play a significant role in expanding our understanding of the intricate world of cellular functions and membrane dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A inhibits histone deacetylase (HDAC), which could alter chromatin structure and potentially downregulate IQSEC1 expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase and subsequent mRNA synthesis, which may decrease IQSEC1 levels. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide has been shown to inhibit the transcription of a wide range of genes, which could include the gene encoding IQSEC1. | ||||||
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $67.00 $306.00 | 2 | |
Alsterpaullone is a cyclin-dependent kinase inhibitor, which could disrupt cell cycle progression and potentially downregulate IQSEC1 expression. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Rocaglamide inhibits translation initiation, which may lead to a general decrease in protein synthesis, including that of IQSEC1. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin specifically inhibits eukaryotic RNA polymerase II, which could lead to decreased mRNA synthesis for genes including IQSEC1. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA polymerase II transcription elongation, which may result in reduced expression of IQSEC1. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol inhibits cyclin-dependent kinases, potentially altering the transcription of genes including IQSEC1. | ||||||
Sinefungin | 58944-73-3 | sc-203263 sc-203263B sc-203263C sc-203263A | 1 mg 100 mg 1 g 10 mg | $266.00 $5100.00 $39576.00 $690.00 | 4 | |
Sinefungin is an inhibitor of S-adenosyl-L-methionine-dependent methyltransferases, potentially affecting epigenetic regulation of IQSEC1. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, stressing the ER and potentially leading to a global decrease in protein synthesis, including IQSEC1. | ||||||