Date published: 2025-10-6

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Ion Pair Reagents

Santa Cruz Biotechnology now offers a broad range of ion pair reagents for use in various applications. Ion pair reagents are essential in chromatography, particularly in high-performance liquid chromatography (HPLC), where they enhance the separation of ionic and highly polar compounds. These reagents work by forming ion pairs with the analyte ions, thereby increasing their hydrophobicity and retention on reversed-phase columns. This process improves the separation efficiency and resolution of complex mixtures, which is crucial in analyzing biological samples and environmental pollutants. Researchers use ion pair reagents to achieve better peak shapes, enhanced selectivity, and increased sensitivity in their chromatographic analyses. These reagents are particularly valuable for separating and quantifying small ions, peptides, and nucleotides, providing precise and reproducible results. By offering a comprehensive selection of high-quality ion pair reagents, Santa Cruz Biotechnology supports advanced research in analytical chemistry, biochemistry, and environmental science. These products empower scientists to optimize their chromatographic conditions, leading to improved analytical performance and reliable identification and quantification of target compounds. View detailed information on our available ion pair reagents by clicking on the product name.

Items 1 to 10 of 33 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Tetramethylammonium sulfate

14190-16-0sc-251202
2.5 g
$81.00
(1)

Tetramethylammonium sulfate serves as an effective ion pair reagent, facilitating the solubilization of ionic compounds in organic solvents. Its quaternary ammonium structure enhances ion pairing through strong electrostatic interactions, promoting the formation of stable complexes. This compound exhibits unique solvation properties, allowing for improved reaction kinetics in nucleophilic substitutions. Additionally, its ability to modulate ionic strength can influence reaction pathways, making it a versatile agent in various chemical processes.

Dodecyltrimethylammonium bromide

1119-94-4sc-239839
25 g
$54.00
(1)

Dodecyltrimethylammonium bromide acts as a potent ion pair reagent, characterized by its long hydrophobic alkyl chain that enhances solubility in nonpolar environments. This surfactant facilitates the formation of ion pairs through hydrophobic interactions, stabilizing charged species in organic media. Its unique amphiphilic nature allows for effective micelle formation, which can alter reaction dynamics and enhance the selectivity of nucleophilic attacks, making it a valuable tool in synthetic chemistry.

Sodium decyl sulfate

142-87-0sc-251016
10 g
$207.00
(0)

Sodium decyl sulfate serves as an effective ion pair reagent, distinguished by its unique surfactant properties. The presence of a decyl chain promotes significant hydrophobic interactions, enabling the stabilization of ionic species in aqueous solutions. This compound enhances reaction kinetics by facilitating the solubilization of polar reactants, leading to improved reaction rates. Its ability to form organized structures in solution can also influence the selectivity of various chemical pathways, making it a versatile agent in analytical applications.

Tetrabutylammonium chloride

1112-67-0sc-251150
sc-251150A
25 g
100 g
$68.00
$249.00
1
(0)

Tetrabutylammonium chloride functions as a notable ion pair reagent, characterized by its quaternary ammonium structure that enhances solubility of ionic compounds in organic solvents. Its bulky butyl groups create a hydrophobic environment, promoting the stabilization of charged species. This compound can significantly alter reaction dynamics by modulating ionic interactions, leading to increased reaction rates and selectivity in various chemical processes. Its unique ability to form stable ion pairs makes it a valuable tool in complexation and extraction methodologies.

Tetraheptylammonium bromide

4368-51-8sc-251183
10 g
$99.00
(0)

Tetraheptylammonium bromide serves as an effective ion pair reagent, distinguished by its long heptyl chains that enhance the solubility of ionic species in nonpolar solvents. The extended hydrophobic regions facilitate unique molecular interactions, allowing for the stabilization of charged intermediates. This compound can influence reaction kinetics by promoting specific ion pairing, which can lead to enhanced selectivity and efficiency in various chemical transformations. Its capacity to form robust ion pairs is crucial for optimizing extraction and separation processes.

Sodium 1-decanesulfonate

13419-61-9sc-250989
5 g
$63.00
(0)

Sodium 1-decanesulfonate functions as a versatile ion pair reagent, characterized by its decane chain that enhances the solubility of ionic compounds in organic media. The hydrophobic tail promotes effective molecular interactions, enabling the stabilization of ionic species and facilitating their transport across interfaces. This compound can significantly alter reaction pathways by modulating the electrostatic environment, leading to improved selectivity and reaction rates in various chemical systems. Its unique structure allows for the formation of stable ion pairs, which is essential for enhancing the efficiency of separation techniques.

Tetrakis(decyl)ammonium bromide

14937-42-9sc-251193
10 g
$138.00
(0)

Tetrakis(decyl)ammonium bromide serves as a specialized ion pair reagent, distinguished by its long decyl chains that enhance hydrophobic interactions. This unique structure promotes the formation of stable ion pairs, effectively shielding ionic charges and facilitating their movement in nonpolar environments. The compound's ability to modulate the local dielectric constant can significantly influence reaction kinetics, leading to altered pathways and improved selectivity in various chemical processes. Its distinctive molecular architecture allows for enhanced solubilization of otherwise insoluble ionic species, making it a powerful tool in complex reaction systems.

Dibutylamine acetate Concentrate

19070-91-8sc-257326
sc-257326A
10 ml
100 ml
$56.00
$299.00
(0)

Dibutylamine acetate concentrate functions as a versatile ion pair reagent, characterized by its dual hydrophilic and hydrophobic properties. This unique balance fosters effective solvation of ionic species, promoting their stability in diverse environments. The compound's ability to form transient complexes enhances reaction kinetics, allowing for rapid ion exchange and improved selectivity. Its distinctive molecular interactions facilitate the transport of charged species, optimizing performance in various chemical applications.

Tetrahexylammonium hydrogensulfate

32503-34-7sc-251187
2 g
$140.00
(1)

Tetrahexylammonium hydrogensulfate serves as a specialized ion pair reagent, notable for its ability to stabilize ionic species through strong electrostatic interactions. Its large hydrophobic tetrahexyl groups create a unique environment that enhances solubility and facilitates the formation of ion pairs. This compound exhibits remarkable selectivity in ion transport, promoting efficient reaction pathways and accelerating kinetics in complex mixtures, making it a valuable tool in various analytical processes.

Sodium 1-heptanesulfonate monohydrate

207300-90-1sc-250990
10 g
$102.00
(0)

Sodium 1-heptanesulfonate monohydrate functions as an effective ion pair reagent, characterized by its ability to enhance the solubility of polar compounds in non-polar solvents. The sulfonate group provides strong ionic interactions, promoting the formation of stable ion pairs. This compound's unique hydrophobic heptane chain contributes to its capacity to modulate reaction environments, influencing selectivity and improving the efficiency of ion transport in diverse chemical systems.