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Dodecyltrimethylammonium bromide (CAS 1119-94-4)

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Alternate Names:
Lauryltrimethylammonium bromide
Application:
Dodecyltrimethylammonium bromide is a useful biochemical for proteomics research
CAS Number:
1119-94-4
Molecular Weight:
308.34
Molecular Formula:
C15H34N•Br
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dodecyltrimethylammonium bromide is a cationic surfactant widely used in research areas such as colloid and interface science. Its ability to form micelles in aqueous solutions makes it useful for studying the physicochemical properties of surfactant aggregates, which are relevant to the behavior of many biological and industrial systems. In the study of membrane mimetics, Dodecyltrimethylammonium bromide is often employed in the formation of model cell membranes to understand the interaction between surfactants and lipid bilayers. Additionally, it is used in the synthesis of nanoparticles, where it acts as a stabilizing agent to control particle size and prevent aggregation. Researchers also investigate the antimicrobial properties of this compound, examining its efficacy in disrupting bacterial membranes and the potential mechanisms behind this activity. Furthermore, Dodecyltrimethylammonium bromide serves as a phase transfer catalyst in organic synthesis, aiding in the transfer of a reactant from one phase into another, where the reaction occurs.


Dodecyltrimethylammonium bromide (CAS 1119-94-4) References

  1. Binding of dodecyltrimethylammonium bromide to pH-responsive nanocolloids containing cross-linked methacrylic acid-ethyl acrylate copolymers.  |  Wang, C., et al. 2004. Langmuir. 20: 7933-9. PMID: 15350055
  2. Effects of interactions on the formation of mixed micelles of 1,2-diheptanoyl-sn-glycero-3-phosphocholine with sodium dodecyl sulfate and dodecyltrimethylammonium bromide.  |  Vautier-Giongo, C., et al. 2005. J Colloid Interface Sci. 282: 149-55. PMID: 15576093
  3. Adsorption of dodecyltrimethylammonium bromide and sodium bromide on gold studied by liquid chromatography and flow adsorption microcalorimetry.  |  Király, Z., et al. 2006. Langmuir. 22: 3207-13. PMID: 16548579
  4. Determination of partial unfolding enthalpy for lysozyme upon interaction with dodecyltrimethylammonium bromide using an extended solvation model.  |  Behbehani, GR., et al. 2008. J Mol Recognit. 21: 132-5. PMID: 18383101
  5. Morphology characterization and single-molecule study of DNA-dodecyltrimethylammonium bromide complex.  |  Ran, SY., et al. 2011. J Phys Chem B. 115: 4568-75. PMID: 21469675
  6. Physicochemical properties of methylcellulose and dodecyltrimethylammonium bromide in aqueous medium.  |  Villetti, MA., et al. 2011. J Phys Chem B. 115: 5868-76. PMID: 21517042
  7. Spectrometric study on the interaction of dodecyltrimethylammonium bromide with curcumin.  |  Ke, D., et al. 2011. Langmuir. 27: 14112-7. PMID: 22004075
  8. Micellization of dodecyltrimethylammonium bromide in water-dimethylsulfoxide mixtures: a multi-length scale approach in a model system.  |  Peyre, V., et al. 2013. J Colloid Interface Sci. 389: 164-74. PMID: 23039925
  9. Volumetric and viscometric studies on dodecyltrimethylammonium bromide in aqueous and in aqueous amino acid solutions in premicellar region.  |  Hossain, MF., et al. 2010. Monatsh Chem. 141: 1297-1308. PMID: 26166851
  10. Self-assembly of sodium dodecylsulfate and dodecyltrimethylammonium bromide mixed surfactants with dyes in aqueous mixtures.  |  Sachin, KM., et al. 2019. R Soc Open Sci. 6: 181979. PMID: 31032045
  11. Dodecyltrimethylammonium bromide surfactant effects on DNA: Unraveling the competition between electrostatic and hydrophobic interactions.  |  Silva, EF., et al. 2020. Phys Rev E. 102: 032401. PMID: 33076016
  12. Percutaneous absorption of dodecyltrimethylammonium bromide, a cationic surfactant, in the rat.  |  Bartnik, FG. and Wingen, F. 1979. Food Cosmet Toxicol. 17: 633-7. PMID: 546698
  13. Somatostatin-detergent interaction.  |  Holladay, LA. and Wilder, P. 1980. Biochim Biophys Acta. 629: 156-67. PMID: 6102870

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dodecyltrimethylammonium bromide, 25 g

sc-239839
25 g
$54.00