Inv Inhibitors
Chemical inhibitors of Inv target the protein by interfering with the cyclin-dependent kinases (CDKs) that are crucial for the phosphorylation events which Inv regulates within the cell cycle. Alsterpaullone can inhibit Inv by obstructing these kinases, leading to a functional inhibition of Inv's role in cell cycle progression. Similarly, Roscovitine serves by targeting kinases essential for Inv's regulatory actions, thereby disrupting Inv's functionality. Purvalanol A impedes the activity of kinases that Inv modulates, while Indirubin-3'-monoxime disrupts kinase activity necessary for Inv-mediated cell cycle transitions. Olomoucine interferes with the kinase's ability to phosphorylate substrates critical for Inv's function in cell cycle regulation, further exemplifying the direct kinase interference strategy employed by these chemical inhibitors.
Continuing with this theme, Flavopiridol prevents the phosphorylation of proteins that Inv influences, which is a crucial step in Inv's role in cell cycle processes. Butyrolactone I targets the kinases that Inv acts upon, blocking the cell cycle progression that Inv is implicated in. UCN-01 suppresses kinase activity required for the cellular functions controlled by Inv, including cell cycle checkpoints. SNS-032 halts the kinase activity upon which Inv relies to exert its effects on cell cycle progression. Dinaciclib blocks the activity of kinases essential for the phosphorylation processes associated with Inv in cell cycle regulation. AZD5438 attenuates the activity of kinases, thereby inhibiting Inv's functions related to cell cycle control. Finally, SU9516 prevents kinase activity necessary for the cellular processes that Inv regulates, focusing specifically on cell cycle checkpoints. Each of these chemicals can inhibit Inv by specifically targeting the cellular mechanisms and pathways that are essential for Inv's operational role in cell regulation.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $68.00 $312.00 | 2 | |
Alsterpaullone is a cyclin-dependent kinase inhibitor that can inhibit Inv by obstructing the cell cycle-related kinases which Inv is known to interact with, leading to a functional inhibition of Inv's role in cell cycle progression. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
Roscovitine serves as an inhibitor to multiple cyclin-dependent kinases and can inhibit Inv by targeting those kinases which are essential for the phosphorylation events that Inv regulates within the cell cycle. | ||||||
Purvalanol A | 212844-53-6 | sc-224244 sc-224244A | 1 mg 5 mg | $72.00 $297.00 | 4 | |
Purvalanol A, another cyclin-dependent kinase inhibitor, can inhibit Inv by impeding the activity of the kinases Inv modulates, resulting in the disruption of Inv's involvement in cell cycle control. | ||||||
Indirubin-3′-monoxime | 160807-49-8 | sc-202660 sc-202660A sc-202660B | 1 mg 5 mg 50 mg | $79.00 $321.00 $671.00 | 1 | |
Indirubin-3'-monoxime is a potent inhibitor of cyclin-dependent kinases, and it can inhibit Inv by disrupting the kinase activity necessary for Inv-mediated cell cycle transitions. | ||||||
Olomoucine | 101622-51-9 | sc-3509 sc-3509A | 5 mg 25 mg | $72.00 $274.00 | 12 | |
Olomoucine, a selective inhibitor of certain cyclin-dependent kinases, can inhibit Inv by interfering with the kinase's ability to phosphorylate substrates that are critical for Inv's function in cell cycle regulation. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
Flavopiridol inhibits various cyclin-dependent kinases and can inhibit Inv by preventing the phosphorylation of key proteins that Inv is known to influence, thereby inhibiting Inv's role in cell cycle processes. | ||||||
Butyrolactone I | 87414-49-1 | sc-201533 sc-201533A | 200 µg 1 mg | $122.00 $514.00 | 1 | |
Butyrolactone I is a selective inhibitor of cyclin-dependent kinases and can inhibit Inv by targeting the kinases that Inv acts upon, thus blocking the cell cycle progression that Inv is implicated in. | ||||||
UCN-01 | 112953-11-4 | sc-202376 | 500 µg | $251.00 | 10 | |
UCN-01, a staurosporine analog, inhibits protein kinase C and can inhibit Inv by suppressing the kinase activity that is required for the cellular functions controlled by Inv, including cell cycle checkpoints. | ||||||
SNS-032 | 345627-80-7 | sc-364621 sc-364621A | 5 mg 10 mg | $169.00 $262.00 | ||
SNS-032 is a CDK inhibitor with the ability to inhibit Inv by halting the kinase activity that Inv relies on to exert its effects on cell cycle progression and checkpoint controls. | ||||||
Dinaciclib | 779353-01-4 | sc-364483 sc-364483A | 5 mg 25 mg | $247.00 $888.00 | 1 | |
Dinaciclib, a potent CDK inhibitor, can inhibit Inv by blocking the activity of kinases that are essential for the phosphorylation processes Inv is associated with in cell cycle regulation. | ||||||